ACETO ACETIC ESTER 97 



Alcoholic ammonia acts on it to form a body C 7 H I5 N 3 O 3 , which 



/ NHCONH 2 

 may be represented thus : CH 3 C / NH 2 and which is 



^CHC-OH 



\OC 2 H 5 



; ?-uramidocrotonic amid together with one molecule of alcohol. 

 Boiling this with water decomposes it into urea, acetone, alcohol, car- 

 bon dioxid and ammonia. 



MEWES, W., 1888. 



Ann. Chem. 245, 58-84 ; J. Chem. Soc. 54 .817 ; Ber. 21, 473 (C). 



Halogen Substitution Products of Acetoacetic Ester 



and their Behavior with Sodethoxid. 



Passing chlorin through acetoacetic ester produces the mono-, di-, 

 tri- and tetra-chlor-acetoacetic esters which boil at 194, 2O5-2O7, 223- 

 225, and 245-25o respectively. Some difficulty was found in entirely 

 separating them from one another. The bromo-chlor- acetoacetic esters 

 were formed by treating the chlor-acetoacetic esters with bromin and 

 also by treating the bromo-acetoacetic esters with chlorin. Sodethoxid 

 decomposes all of the halogen derivatives forming the mono- or di- 

 halogen acetic esters. Bromoacetoacetic ester with Sodethoxid yields 

 succinosuccinic ester. When the chlorobrom-substitution products are 

 treated with sodethoxid, sodium bromid is always formed. 



KNORR, L., 1888. 



Ann. Chem. 245, 357-382 ; J. Chem Soc. 54. mi ; Ber. 21, 628 (C). 

 Synthetical Researches on Acetoacetic Ester. Part IV. 



Methyl-acetoaceticanilid, CH 3 COCH (CH 3 ) CONHC 6 H 5 , which was 

 prepared from methyl-acetoacetic ester and anilin, melts at 138 to 140. 

 Sulfuric acid changes it into dimethyl-carbostyril [3' 14'], a weak acid 

 from which the dimethyl product C 9 H 4 OH (CH 3 ) 2 N was obtained. 

 Chlor-dimethyl-quinolin [Cl : (CH 3 ) 2 =2':3':4'], ortho- [4': i], meta-and 

 para- [4' : 3] dimethyl-quinolin were described together with some phenyl ; 

 nitrogenous derivatives. 



