PYOGENIC COCCI 163 



Bouillon. Turbid, with sediment. 



A gar. Pearly white growths. 



Potato. Slight invisible growth. 



Stained by ordinary anilin dyes. Gram negative. 



Glucose broth, unfermented. 



Milk made alkaline. 



The disease may be produced in monkeys by even small 

 amounts of pure culture. In man a chronic, remittent febrile 

 disease is produced, with sweating and arthritis. The mor- 

 tality is 2 per cent. A reaction can be obtained and is 

 diagnostic. 



Agglutination 1:30 dilution of serum will give positive 

 result, but the complement-fixation test considered more cer- 

 tain (which see}. 



Flies an agency for transmission. 



Mode of Transmission. Zammitt found that 50 per cent, 

 of the goats of Malta gave the agglutination reaction to the 

 micrococcus, and it was present in the milk in 10 per cent. 

 Monkeys fed on the milk contracted the disease. 



Preventive measures instituted in 1906 have borne out the 

 theory that the milk of goats is the cause of Malta fever, and 

 since the practice of importing goats from Malta has stopped, 

 the disease has disappeared from Gibraltar. In Malta, 

 among the troops, the fever has been greatly reduced by 

 eliminating milk from the dietary. 



CHAPTER XXm 

 PYOGENIC COCCI 



NEARLY all micro-organisms can produce suppuration, but 

 in the acute abscesses occurring in the skin and lymphatics and 

 accompanying all pus affections are found groups of micro- 

 cocci so regularly that they have been designated as the pus- 

 forming or pyogenic cocci. The two most important mem- 



