THE MICRO-ORGANISM OF SYPHILIS AND ALLIED ORGANISMS 2OQ 



cells of the blood, the smaller ends of pear in opposition; 

 coarse ameboid movement. 



Transmission. An insect or tick (Boophilus bovis) be- 

 comes infected, and by its bite infects other animals. 



Other similar sporozoa have been found in animal diseases 

 and in man in Rocky mountain fever. The P. hominis has 

 been described, but not definitely determined. 



Rabies or Hydrophobia. Negri Bodies (Negri, 1903). 

 Origin. Found in the nervous system of animals dying of 

 rabies (hydrophobia). 



Form. Round and oval, hyaline bodies, with a sharp out- 

 line and containing a nucleolus. The plasma is slightly 

 granular. They are regarded as protozoa. 



Staining. A smear from brain tissue is made on a cover- 

 glass and fixed in methyl-alcohol for five minutes ; then stained 

 by Giemsa; stain for half-hour to three hours. 



All mammals susceptible; man chiefly from bite of dog. 

 Only a small percentage of persons bitten by rabid dog be- 

 come infected 16 per cent. 



The virus resides in the saliva, and also in the central 

 nervous system. The Pasteur preventive is an accepted fact, 

 and depends for its power on a form of active immunization. 

 The virus used is obtained from dried spinal cord of infected 

 rabbits, gradually increasing the virulence, older cords first 

 used and then cords exposed to drying for lesser time. 



CHAPTER XXVIII 



THE MICRO-ORGANISM OF SYPHILIS AND ALLIED 

 ORGANISMS 



Spirochaeta Pallida (Schaudinn, 1905). Spironema 

 Pallidum; Treponema Pallidum. Found in hereditary syph- 

 ilis in all organs, in chancre, and lymphatic glands, and in 

 secondary lesions, mucous patches, in the internal organs, 



