LECTURE III. 



enlargement of its individual cells. In this case there 

 is real hypertrophy without, properly speaking, any 



FIG. 27. 



new formation. Essentially different from this process 

 are the cases in which an enlargement takes place in 

 consequence of an increase in the number of the elements. 

 A liver, namely, may also become enlarged by a very 

 abundant development of a series of small cells in the 

 place of the ordinary ones. Thus, when simply hyper- 

 trophied, we see the panniculus adiposus of the skin swell 

 up in consequence of every single fat-cell's absorbing a 

 larger quantity of fat than usual, and when this takes 

 place in thousands upon thousands, nay, we may say, 

 in hundreds of thousands and millions of cells, the re- 

 sult is very obvious and strikes the eye (polysarcia). 

 but it is just as possible for new cells to form in addi- 

 tion to the old ones, and for an increase of size to take 

 place without any enlargement of the individual cells. 



Fig. 27. Diagrams of hepatic cells. A. Their simple physiological appearance. 

 B. Hypertrophy : a, simple ; 6, with accumulation of fat (fatty degeneration, fatty 

 liver). Q. Hyperplasy (numerical or adjunctive hypertrophy), a. Cell with nucleus 

 and divided nucleolus. b. Divided nuclei, c, c. Divided cells. 



