228 LECTURE IX. 



as different numbers throughout the parenchyma of the 

 spleen, as the solitary and Peyerian follicles in the intes- 

 tine. In a section through the spleen we see the trabe- 

 culae radiating from the hilus towards the capsule and 

 enclosing certain districts of glandular substance, within 

 which the red spleen pulp lies, interrupted here and thero 

 by a sometimes greater, sometimes less, number of white 

 bodies (follicles) of larger or smaller size, single or in 

 groups, and sometimes almost clustered. The structure 

 of these follicles agrees exactly with that of the follicles 

 of lymphatic glands. 



We may therefore regard this whole series of appara- 

 tuses as nearly equivalent to the lymphatic glands pro- 

 perly so called, and a swelling of the spleen will, under 

 certain circumstances, furnish just as abundant a supply 

 of colourless blood-corpuscles, as is the case when a 

 lymphatic gland enlarges. This possibility explains how 

 it is that, for example, in cholera, where the change in 

 the solitary glands and Peyer's patches forms the chief 

 part of the disease, and where the swelling of the other 

 lymphatic glands is much less marked, we meet at an 

 extremely early period with a considerable increase in 

 the colourless corpuscles. Hereby is explained moreover 

 why, in such cases of pneumonia as are connected with 

 great swelling of the bronchial glands, an increase in the 

 number of colourless blood-corpuscles likewise takes 

 place, which is generally wanting in those forms of pneu- 

 monia which are not connected with such swelling. The 

 more the irritation extends from the lung to the lymph- 

 atic glands, the more abundantly noxious fluids are con- 

 veyed from the lung to the glands the more manifestly 

 does the blood undergo this change. 



Upon examining these different pathological processes 

 in this manner one by one, it is really impossible to dis- 

 cover anything at all, which in a morphological point of 



