LECTURE XVI. 



APRIL 14, 1858. 

 A MORE PRECISE ACCOUNT OF FATTY METAMORPHOSIS. 



Fatty degeneration of muscles Fatty metamorphosis of the substance of the heart 

 Formation of fat in the muscles in distortions. 



Corpus luteum of the ovary Fatty metamorphosis of pulmonary epithelium Yel- 

 low softening of the brain Arcus senilis. 



Optical properties of fattily degenerated tissues Renal epithelium in Bright's dis- 

 ease Successive stages (cloudy swelling, fatty metamorphosis, fatty detritus 

 [debris], atrophy) Inflammatory globules Similarity of the result in inflam- 

 matory and non-inflammatory changes. 



Atheromatous process in arteries Its relation to ossification Inflammatory cha- 

 racter of the process ; its analogy with endocarditis Formation of the athe- 

 romatous deposit Appearance of cholestearine Arterio-sclerosis Endoarte- 

 ritis Calcification and ossification of arteries. 



Mixed, active-passive processes. 



TO-DAY, gentlemen, I have sent round a few specimens 

 of fatty degenerations, in part to serve as a supplement 

 to what you saw at the last lecture. 



One or two of these preparations are intended to dis- 

 play the fatty degeneration of the substance of the heart. 

 You will observe that, even with the naked eye, certain 

 changes can be recognized in the heart, namely, a disco- 

 loration of its whole substance (which no longer presents 

 the red hue of muscle, but wears a pale yellow tint), and 

 besides peculiar spots on the papillary muscles. If you 

 examine these more closely, you will perceive, in the 

 direction of the primitive fasciculi, short, yellowish 



