FATTY DEGENERATION OF MUSCLES. 335 



limbs, as for example, in the different kinds of club-foot. 

 In these it generally turns out, that, in the parts corres- 

 ponding to the yellow streaks, there is not only a real 

 transformation of the muscular substance, but that an in- 

 terstitial development of adipose tissue has also nearly 

 constantly taken place there, so that it lies in rows be- 

 tween the primitive muscular fasciculi, and thereby pro- 

 duces a striation which looks yellowish to the naked eye, 

 and is due to an arrangement very similar to that which 

 gives rise to the red striation of genuine muscular tissue.* 

 This is precisely how matters stood in the case I spoke 

 of recently (p. 364, Fig. 108), where we found a row of 

 fat-cells between every two primitive fasciculi ; the yel- 

 low that you saw there, was not altered muscle, but a 

 mass of fat which had grown in between the muscular 

 fibres. But in addition to such interstitial adipose tissue 

 there is in the case now before us a parenchymatous de- 

 generation in the same muscle ; the substance of the mus- 

 cle is also really in a state of fatty degeneration. The 

 degenerated fibres are, however, only to be seen with 

 the naked eye in the lower parts of the muscle, whilst 

 the portion which lay in immediate Contact with the 

 greatest projection of the thorax and had been subjected 

 to the greatest tension, to the naked eye presents no 

 trace of muscular tissue. Under the microscope, how- 

 ever, we even there find isolated muscular fibres lying 

 close to one another and still distinctly transversely stri- 

 ated, and others plentifully filled with fat. You see, 

 therefore, that these are two different conditions j the 

 one form, where the muscle is interrupted in the course 

 of its primitive fasciculi by degenerated places, and where 



* For, as each row of fat-cells lies between two primitive fasciculi (Fig. 108), the 

 fat (like the substance of the fasciculi, the cyntonine) has a layer of sarcolemma 

 upon each side of it, so that, if the syntonine atrophies, the fat appears to have 

 taken its place and to lie within the primitive fasciculi, and many well known au- 

 thors have taken this to be the case. From a MS. Note by th* Author. 



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