86 C. WINKLER. THE CENTRAL COURSE 



thai with NISST/S method used a fortnight after removal of the 

 cochlea or after root-section , were not shown any degenerative 

 changes in the cells of the nuclei , neither in the tuberculum , nor 

 in the nucleus ventralis or in the olivae or nuclei trapezoides. 



But in cases of atrophy the question stands otherwise. As regards 

 the tuberculum acusticum , for instance there certainly never occurs 

 any atrophy of the large cells. 



A preparation made on purpose to judge the cells in that nucleus, 

 for instance a NISSL preparation of the normal one (Plate VI fig. C) 

 may show, that l e in the superficial medullated as well as in the 

 grey layers, small cells of spherical and pyramidal shape are scattered. 



2 e the large pyramidal-shaped cells are found in the middle grey layer. 



3 smaller pyramidal-shaped cells do appear in the deeper strata. 



The more profoundly the layer is searched , the smaller the 

 cells are found to be , their prevailing shape becoming spherical or 

 elliptical, and their longest axis lying in the direction of the longi- 

 tudually sectioned fibres of the stratum medullare profundum. These 

 elliptical-shaped cells are increasing in number towards the distal 

 pole of the nucleus, and in its neighbourhood, somewhat laterally 

 situated between tuberculum and ventral nucleus, they are accu- 

 mulated in such a manner that a true nucleus is formed. This 

 accumulation is described as the ,,nucleus proprius rand dorsalis". 

 This nucleus continues towards the stratum profundum of the tuber- 

 culum, it also sends prolongations along the lateral and medial 

 borders of the ventral nucleus, embracing it, and at the distal end 

 of this nucleus (Plate VII fig. 7 F and G) the number of the 

 small cells is again much augmented. 



In the ventral nucleus cells of triangular and multipolar shape 

 are found, having nearly the same size of the larger pyramidal cells 

 in the tuberculum. 



Now, for the tuberculum acusticum I agree with nearly all the 

 elder investigators, that in cases of atrophy after rootsection , I 

 never have seen any change in the large pyramidal cells, ranged 

 in radiar lines in the medial grey layer. On the contrary the small 

 cells in the deeper layers are disappearing in great number and in 

 the same time indeed nearly all cells of the nucleus proprius are gone. 



In NissL-preparations however the large cells of the tuberculum are 

 not altered even months after rootsection. And yet after a section 

 through the dorsal system in four days all these large cells are swol- 

 len, their tigroid is desintegrated , briefly they show chromatolysis. 



Now GoLGi-method shows easily that the large pyramidal cells 

 send their axones towards the stria acustica and VON MONAKOW 



