34 Comparative Studies 



proper blood-serum culture medium on which to grow the 

 cultures, and advises comparing all cultures with a cul- 

 ture of the L/offler bacillus grown on the same culture me- 

 dium, under the same conditions. 



He found that at times the polar granules of the diph- 

 theria bacillus appear later than sixteen hours, and with 

 the xerosis bacilli earlier than twenty-four hours, and states 

 that repeated examinations may be necessary to make a 

 positive diagnosis. 



Kruse (43) under bacillus pseudo-diphthericus (Pseudo- 

 diphtherie, Xerose bacillus), classes bacilli which resemble 

 the diphtheria bacillus, but are not pathogenic. Besides 

 the studies already reported, he quotes Zarinke (^Central- 

 blatt fur Bacteriologie, Bd. VI, s. 6), Beck (Zeitschr. fur 

 Hygiene, Bd. VIII), N. Klein (Centralblatt fur Bacteria- 

 logie, Bd. VII, s. 16), Goldscheider (ref. Baumgarten's 

 Jahrbericht. 92) Bscherich (Diphtheric, Wien, 94), Pflugger 

 (Archiv fur Ophthal., 37), Kick (Micro-organismen in Kon- 

 junctivalsack, Wiesbaden, 87), who also report on studies 

 on these organisms, which occur in 30 per cent to 60 per 

 cent of the mouths and noses of all persons, but more 

 frequently still on the normal or diseased conjunctiva. 

 They occur in great masses in xerosis conjunctiva. 



Kruse places in this group also the bacillus striatus 

 albus isolated by v. Besser from the nose of healthy per- 

 sons. Likewise the bacilli found by Wilde (Bonn Hyg. 

 Institui) in the secretion of a case of ozena, and the organ- 

 ism found by Ortman (Berlin klin. Wochenschrift, 89) in 

 a diphtheritic deposit on the mucous membrane of the 

 vaginae of pregnant women, and those found by Rugen- 

 berg (Bonn Hyg. Institut) in four cases of impetigo. He 

 states that possibly the bacillus nodosus parvus which 

 lyustgarten isolated from the urethra belongs to this 

 group, or is identical. Also, bacillus endocarditis griseus 

 of Weichselbaum, and bacillus erythematis uroglini of 

 Demme. 



