338 DR. BENCE JONES ON THE VARIATIONS IN 



The next point was the effect of exercise. 



(13.) Nothing was taken from dinner on the previous day to dinner this day; both 

 meals consisted of mixed diet of meat, bread, and potatoes. The exercise was mo- 

 derate, between three and six o'clock. 



(14.) Nothing was taken since dinner on the previous day until dinner at six; 

 mixed diet with more bread. Exercise also greater between 3 and 5J o'clock. 



Earthy phosphates. Spec. gr. Alkaline phosphates. 



3 o'clock -36 per 1000 urine 1025-4 5-69 



6 o'clock 1 027-1 total phos. per 1 000 urine 778 



lOj at night 1-37 1032*5 5-50 



(15.) Nothing was taken since dinner on the previous day, which consisted of meat 

 only, with distilled water and wine. Very strong exercise was taken between 3 and 

 5 J, the pulse always above 100. 



Earthy phosphates. Spec. gr. Alkaline phosphates. 



11 J o'clock -52 per 1000 urine 10229 3-04 



3 o'clock -36 1026-9 4*36 



5 J o'clock 1028-9totalphos. per 1000 urine 6-81 



In these experiments, the water, which was secreted longest after food, was not in 

 sufficient quantity to admit of the determination of the earthy as well as alkaline 

 phosphates. In all the experiments which were previously made, the exercise was 

 always most between 3 and 6 o'clock, and yet at this time the earthy phosphates were 

 always present in smallest quantity ; so that the quantity of earthy phosphates does 

 not appear to be quickly influenced by exercise. 



The total quantity of phosphates which was found in the water secreted longest 

 after food, and during strong exercise, was about one-third more than the total 

 quantity previously present. This considerable increase so long after food, leads to 

 the conclusion that the amount of alkaline phosphates is influenced by exercise, 

 though, as appears from the previous experiments, not to the same extent as by the 

 kind of food which is taken. 



III. I pass now to the influence of different medicinal substances on the amount of 

 earthy phosphates excreted. 



(16) Breakfast as before, at 9 o'clock. 15 grains of chloride of calcium taken 

 in about an ounce of distilled water at 3 o'clock. 



Earthy phosphates. Spec. gr. 



3 o'clock ^30 per 1000 urine 1024-6 



5J o'clock -22 1016-4 



