Sidney Klein 329 



It seems clear from these facts that the cells of Paneth are specific 

 elements engaged in the secretion of a special substance, probably an 

 enzyme which is of use in digestion. It is not, however, possible to con- 

 nect the Paneth cells with the formation of the new substances, secretin, 

 erepsin, and enterokinase, because these substances are also found in the 

 small intestine of carnivora in which Paneth cells do not occur. Nor is 

 it possible to connect them definitely with any particular class of food, 

 as Moller suggests, because they have been found not only in herbivorous 

 and granivorous animals, but also in insectivora. 



In conclusion, I wish to express my indebtedness to Professor Bensley, 

 at whose suggestion and under whose direction the work was undertaken, 

 for friendly guidance and advice during the progress of the investigation. 



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