CHAPTER II 

 Dissociation-Products 



tViTH the view of throwing light on the constitution of albumins,, 

 albuminous substances have been dissociated up to a point where they 

 lose their chemical character, and the various dissociation-products so- 



>b+ 'ned have been carefully investigated. Albumins have been boiled 



vith acids and alkalies ; fused with potash ; acted upon by superheated 

 f team ; by ferments derived from animals and plants and subjected to 

 Bacterial action. The changes which are induced in albumins during 



he metabolism of animals and plants under normal and pathological 



onditions have also been studied. 



As the result of dissociation there are obtained, primarily, a number 

 f substances which still resemble the mother substance because both 

 ossess, more or less, the same chemical constitution. The primary 

 issociation - products include such bodies as the albumoses, the 

 eptones, and the peptids. These by further dissociation break up 

 i ito entirely different groups of bodies, the so-called crystalline or 



biuretic decomposition-products. Neither of the two names just 

 rientioned is, however, still correct, since we now know of both 



rystalline albumins and peptones, and of substances which, when 

 laced in series, form a complete chain, one end of which is formed 

 y the peptones giving the biuret-reaction, while the other end is- 

 epresented by simple non- albuminous dissociation -products. It is 

 herefore best to call the non -albuminous dissociation -products the 

 simple dissociation-products.' 



A. PRIMARY DISSOCIATION -PRODUCTS 



Amongst the dissociation-products a special position is occupied by 

 ,hose which are obtained by boiling albuminous substances with hydro- 

 chloric or sulphuric acids or subjecting albumins to the action of such 

 ferments as trypsin. The products formed hereby are the * primary 

 iissociation-products,' in which the carbon chain remains intact, and in 

 which, as far as we know, the nitrogen does not change its position 



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"BRA* 

 or THE 



UNIVERSITY 



