ii PRIMARY DISSOCIATION-PRODUCTS 51 



Oxyphenyl ethylamin, C 8 H n ON 



HO<OCH 2 .CH 2 .NH 2 . 



It is derived from ty rosin by a splitting off of a CCX, group. 1 It has 

 been found by Emerson 2 amongst the products of autodigestion of the 

 pancreas, and by Langstein 3 amongst the final products of peptic 

 digestion. 



26. Tryptophane, or Indol-amino-propionic Acid, C n H 12 N 2 2 . 

 (The constitutional formula is given below.) 



Nencki, 4 and Kiihne, 5 and, later on, particularly E. and H. 

 Salkowski, 6 found amongst the products of putrefying albumin the 

 substances indol and skatol, and their derivatives skatol-carboxylic 7 

 and skatol-acetic acids. 4 8 



H A CH 



Cv f x C. 



CH 







H V H 



Indol. Skatol 



(or jS-methyl-indol). 



CH 3 



J ^>C . COOH | >C . CH 2 . COOH 



H V H 



Skatol-carboxylic acid. Skatol-acetic acid. 



The mother -substance of these bodies Nencki and Salkowski 9 

 believed to be skatol-amino-acetic acid. 



1 R. Schmitt and 0. Nasse, Ann. d. Chem. u. Pharm. 133. 311 (1865). 



2 R. L. Emerson, Hofmeisters Beitr. 1. 501 (1902). 



3 L. Langstein, ibid. 1. 507 (1901). 



4 M. Nencki, Ber. d. deutsch. chem. Ges. 7. II. 1593 (1874), 8. I. 336 (1875), 

 10. I. 1032 (1877) ; Monatshefte f. Chem. 1O. 506, 526, 862, 864, 908(1889). 



5 W. Kiihne, Ber. d. deutsch. chem. Ges. 8. I. 206 (1875). 



6 E. and H. Salkowski, Zeitschr. /. physiol. Chem. 8. 417 (1884), 9. 8 (1884), 9. 

 491 (1885). 



7 E. and H. Salkowski, Ber. d. deutsch. chem. Ges. 13. I. 189 (1880) ; 13. II. 

 2217 (1880). 



8 E. Salkowski, Zeitschr. f. physiol. Chem. 27- 309 (1899). 



9 E. Salkowski, Die Lehre vom Earn, p. 26 (1882) ; Ber. d. deutsch. chem. Ges. 34. 

 Ill; 3884 (1901). 



