178 CHEMISTRY OF THE PROTEIDS CHAP. 



the hetero-albumose radical, all other albumins on being digested 

 yield the same albumoses although in very different amounts. 



For the examination of albumoses it is customary to use the 

 'peptonum siccum' of F. Witte in Rostock, which consists for the 

 greater part of albumoses. It is said to be manufactured by 

 digesting fibrin with artificial gastric juice, but nothing definite is 

 known about it. 1 The first publications of Kiihne 2 as well as those 

 of Pick 3 and Haslam deal with Witte's peptone, while Siegfried pre- 

 pared his own peptone directly from fibrin. According as to whether 

 an albumose is prepared from globulin, vitellin, myosin, gelatine, fibrin, 

 etc., it is called a globulose, vitellose, myosinose, gelatose, fibrinose, 

 etc. ; albumoses, according to this nomenclature, would be only the 

 dissociation -products of egg- and of serum-albumin, but the term 

 albumose is still generally used to include the products of the other 

 albumins. 



Chittenden has called the albumoses derived from serum- and 

 egg-albumin by the name of proteoses. 



I. THE ALBUMOSES AND PEPTONES OBTAINED BY PEPTIC 



DIGESTION 



Albumoses 



Albumoses formed by processes other than those of peptic and 

 tryptic digestion have but rarely been examined. Tryptic digestion 

 rapidly converts albumoses and peptones into simpler compounds, and 

 therefore peptic digestion is more suitable for the study of the 

 dissociation-products of albumins. Meissner 4 and Briicke 5 were the 

 first to investigate gastric digestion ; they were followed by Kiihne 6 

 and his pupils, 7 in special by Neumeister. 8 Kuhne's researches 



1 M. Siegfried, Zeitschr. f. physiol. Cheat. 35. 179 (1902). 



2 W. Kiilme and R. H. Chittenden, Zeitschr. f. Biol. 20. 11 (1884). 



3 E. P. Pick, Zeitschr. f. physiol. Chem. 24. 246 (1897), 28. 219 (1899) ; 

 Hofmeister's Beitrage, 2. 481 (1902). 



4 G. Meissner, Zeitschr. f. ration. Medizin, 7. 1 (1859), 8. 280 (1860), 10. 1. 

 (1861), 12. 46 (1861), 14. 78 (1862), 14. 303 (1862). 



5 E. Briicke, Sitzungsber. d. Wiener Akad., math.-naturw. El. 37. 131 (1859). 



e W. Kiihne, Verh. d. Heidelberger naturh.-ined. Vereins (N.F.) 3. 286 (1885); 

 W. Kiihne and R. H. Chittenden, Zeitschr. f. Biol. 19. 159 (1883) ; W. Kiihne and 

 R. H. Chittenden, ibid. 20. 11 (1884), 22. 423 (1885) ; W. Kiihne, ibid. 29. 1 (1892), 

 29. 308 (1892). 



7 S. Wenz, ibid. 22. 1 (1886) ; E. H. Chittenden and R. Goodwin, Journ. of Physiol. 

 12. 34 (1891). 



8 R. Neumeister, Zeitschr. f. Biol. 23. 381 (1887), 24. 267 (1888), 26. 324 

 (1890) ; Lehrbuch der physiol. Chem. 2nd edition, p. 228 ff. (1897). 



