y ALBUMOSES 183 



j Umber l and Zunz ; 2 casein by Alexander 3 and Zunz ; 2 Bence- Jones' 

 body by Magnus-Levy; 4 bile-mucin by Brauer 5 and the nucleo-proteids 

 of the pancreas, in part at least, by Umber. 6 



The power of withstanding the action of pepsin is possessed, 

 according to Umber, 6 to a different degree by different albumins : serum- 

 albumin is dissociated more readily than is egg-albumin; the most 

 difficult substance to digest is serum-globulin, according to Umber 6 and 

 E. Fischer and Abderhalden, 7 but this may be due to an admixture of 

 anti- ferment. 8 Smith 9 and Strohmer 10 state that the digestibility 

 of albumins is considerably diminished by heating the dried albumin, 

 and Koterski n says that the same effect is produced by boiling watery 

 solutions. 



Some other properties of albumoses, not recorded in the table on 

 p. 180, are the following : 



The protalbumose is very soluble in water, according to Pick, 12 and 

 even more soluble in dilute alcohol. Precipitation commences with 

 80 per cent alcohol, and is approximately complete only if alcohol-ether 

 is used. They diffuse very quickly, 13 and are precipitated only with 

 difficulty. Nitric acid, the alkaloidal reagents, especially tannic acid, 

 all give precipitates, but these are soluble in an excess of the reagent, 

 a phenomenon generally only met with amongst the peptones. 



The hetero-albumose is very slightly soluble in water, more so in 

 salt -solutions, and very soluble in dilute acids and alkalies. It is 

 precipitated from salt solutions by dilution with water. It has a 

 tendency to pass into the insoluble state, i.e. to coagulate (see p. 191, 

 under Plasteins). It contains, according to Hart, 14 Pick, 15 and Fried- 

 mann, 16 many hexone- bases. Its other dissociation -products have 

 already been enumerated on p. 74. Erb 17 has examined the chloride 



1 F. Umber, Zeitschr. f. physiol. Chem. 25. 258 (1898). 



2 E. Zunz, ibid. 27. 219 (1899). 



3 F. Alexander, ibid. 25. 411 (1898). 



4 A. Magnus-Levy, ibid. 3O. 200 (1900). 



5 L. Brauer, ibid. 40. (1903). 



6 F. Umber, Zeitschr. f. klin. Med. 43. fasc. 3 and 4 (1901). 



7 E. Fischer and E. Abderhalden, Zeitschr. f. physiol. Chem. 39. 81 (1903). 



8 K. Glassuer, Hofmeisters Beitrdge, 4. 79. (1903). 



9 H. Smith, Zeitschr. f. Biol. 19. 469 (1883). 



10 F. Strohmer, Chem. Zentralbl. 1902, II. 971. 



11 T. Kotarski, Zeitschr. f. physiol. Chem. 38. 552 (1903). 



12 E. P. Pick, ibid. 28. 219 (1899). 



13 R. Neumeister, Lehrb. d. physiol. Chem. 2nd edition, Jena, 1897, p. 231, 



14 E. Hart, Zeitschr. f. physiol. Chem. 33. 347 (1901). 



15 E. P. Pick, ibid. 28. 219 (1899). 



16 E. Friedmann, ibid. 29. 50 (1899). 



17 W. Erb, Zeitschr. f. Biol. 41. 309 (1901). 



