IX 



EGG-ALBUMIN 359 



56 , while other authors give higher figures (compare with Ramsden's 

 figures for fibrinogen, p. 382). Hopkins 1 found 



a D = -30-70. 



The dissociation-products have been given on p. 70, No. 5. Its 

 high glticosamin-content is of special importance, and has been definitely 

 established after a long discussion by Miiller and JSeemann 2 and Lang- 

 stein. 8 The latter found at least 10 to 11 per cent glucosamin, while 

 Hofmeister 4 estimates it at 15 per cent. According to Steudel, 5 

 glucosamin is contained in egg-white, as it is in the mucins, as a higher 

 complex. According to Morner, 6 only the smaller part of the sulphur 

 occurs as cystin. There is also present a volatile substance, which is 

 perhaps ethyl sulphide, and if this be so, the ethyl sulphide is derived 

 from cystin, see p. 168. 



lodo-egg-albumin contains about 9 per cent iodine, according to 

 Hofmeister. 4 Blum and Vaubel 7 have not employed pure prepara- 

 tions, but the mixture of egg-white ; Hopkins s and Pinkus found a 

 Br-capacity of 15 '8 per cent for crystalline albumin. The HCl-capacity 

 has been determined by Erb 9 as at most 0'234 grm. pro 1 grm. ; that 

 of egg-white has been investigated by Sjoqvist 10 and Bugarszky and 

 Liebermann. 11 The behaviour of egg-albumin during coagulation has 

 been frequently investigated, especially by Pauli (see p. 285). The so- 

 called "ash-free" albumin (seep. 344) is denaturalised albumin. If 

 hens' eggs are placed for two to three days into 10 per cent KOH, then 

 the egg-white no longer coagulates in the usual way on being boiled, 

 but sets into a vitreous transparent jelly, as the salts are diminished 

 while the alkalies are increased in amount, according to Tarchanoff 12 

 and Zoth. 13 Alcohol and ether denaturalise egg-albumin much more 

 rapidly than serum-albumin, according to Starke. 14 Dissociation by 



1 F. G. Hopkins, Journ. of Physiol. 25. 306 (1900). 



2 F. Miiller and J. Seemann, Deutsche medizin. Wochenschrift, 1899, p. 209 ; J. 

 Seemann, Medizin. Dissertation, Marburg, 1898 ; F. Miiller, Zeitschr. f. BioL 42. 468 

 (1901). * 3 L. Laugstein, Zeitschr. f. physiol. Cheat. 31. 49 (1900). 



4 F. Hofmeister, ibid. 24. 158 (1897). 5 H. Steudel, ibid. 34. 353 (1901). 



6 K. A. H. Morner, ibid. 34. 207 (1901). 



7 F. Blum and W. Vaubel, Journ. /. prakt. Chem. N.F. 57. 365 (1898) ; F. Blum, 

 Zeitschr. f. physiol. Chem. 28. 288 (1893). 



8 F. G. Hopkins, Her. d. deutsch. chem. Ges. 3O. II. 1860 (1897) ; F. G. Hopkins 

 and S. N. Pinkus, ibid. 31. II. 1311 (1898). 



9 W. Erb, Zeitschr. f. Biol. 41. 309 (1901). 



10 J. Sjoqvist, 'Uber Salzsaure,' Skandin., Arch. f. Physiol. 5. 276 (1894). 



11 St. Bugarszky and Liebermann, Pfluger's Arch.f. d. ges. Physiol. 72. 51 (1898). 



12 J. Tarchanoff, ibid. 33. 303 (1884) ; 39. 476 and 489 (1886). 



13 0. Zoth, Wiener Akad. mathemat. Kl. III. 1OO. 140 (1891). 



14 K. V. Starke, Malys Jahresber. 11. 17 (1881). 



