368 



CHEMISTRY OF THE PROTEIDS 



CHAP, 



products considerable amounts of glucosamin and a correspondingly 

 well-marked reaction of Molisch. All the other colour-tests gave also 

 positive results. Its solubility is the same as that of serum-globulin, 

 and the question as to its uniform nature is as little settled as in the 

 case of serum-globulin. Umber 1 obtained egg-globulin, by an accident, 

 once in a crystalline form. Many experiments on the action of salts 

 on albumins refer to this globulin, as the experiments were made 

 with impure egg-albumin, the globulin fraction of which is more 

 readily precipitated than is the albumin fraction. 2 



The percentage composition varies considerably, owing to the 

 difficulty of preparing a pure ovo-globulin. 



5. Lact-Globulin 



It was discovered by Sebelien 3 in milk, and was subsequently 

 also found by Hewlett. 4 Milk contains only a few milligrammes per 

 litre. It resembles serum-globulin both as regards precipitation-limits 

 and coagulation-temperature, 72. Lact-globulin is much more abun- 

 dant in colostrum than it is in milk. 5 



6. Crystalline Globulin from Urine 



Noel Paton 6 found once in the urine of a man suffering from an 

 unknown disease very large quantities of a crystalline globulin in 

 addition to ordinary albumin. Huppert 7 has subsequently brought 

 forward the view that Paton's globulin is in reality a hetero-albumose 



1 F. Umber, Berl. klin. Wochenschr. 1902, No. 28. 



12 W. Panli, Pflugers Arch. f. d. ges. Physiol. 78- 315 (1899) ; Hofmeisters 

 Beitriige, 3. 225 (1902) ; F. Mylius, Ber. d. deutsch. chem. Ges. 36- I- 775 (1903). " 



3 J. Sebelien, Zeitschr. f. physiol. Chem. 9. 445 (1885) ; and hi 7ow?i. of Physiology f 

 12. 95 (1891). 



4 Hewlett, Journ. of Physiol. 13 798 (1892). 



5 J. Sebelien, Zeitschr. f. physiol. Chem. 13. 135 (1888). 



6 Noel Paton, Proc. of the Roy. Soc. of Edinburgh,, 1891-92, p. 102. 



7 Huppert, Zeitschr. f. physiol. Chem. 22. 500 (1896). 



