392 CHEMISTRY OF THE PROTEIDS CHAP. 



* paramyosinogen ' as indicated by heat-coagulation at 47-50, while 

 there is evidence of the presence of abundance of ' myosinogen ' 

 coagulating between 55 and 65." Velichi states that he isolated 

 from the nonstriped muscle of the stomach two proteids : 



1. A globulin, apt to coagulate spontaneously and clotting when 



heated to 54-60. 



2. An albumin, precipitated by heating to 46-50. 



Amongst invertebrates v. Fiirth l and Przibram 2 found substances 

 resembling myosinogen in their reactions, but possessing, as a rule, 

 a somewhat lower heat -coagulation -temperature. In fish-muscles 

 v. Fiirth found * myoproteid ' which is soluble in water, non-coagulable 

 by boiling, but precipitable by strong acids; magnesium sulphate 

 and sodium chloride salt it out, while the precipitation-limits for 

 ammonium sulphate are 4'0 and lO'O. Sodium -hydrate solution 

 does not precipitate even in the presence of salt. It does not 

 contain an appreciable amount of phosphorus, and contains neither 

 a reducing substance nor pseudo-nuclein. 



The muscle of the octopus has been studied by v. Fiirth, 3 and by 

 Henze, 4 who has paid special attention to the extractives and the 

 reserve -materials with the view of establishing some connection 

 between these and the urinary secretion. Octopus muscle contains 

 77*3 per cent water and 13 '13 per cent nitrogen ; the watery extracts 

 contain neither glycogen, urea, hexone-bases or amino-acids, such as 

 glycocoll, nor creatin or creatinin. On the other hand taurin is very 

 abundant, amounting to 0*5 per cent; the purin-bases are represented 

 almost exclusively by hypoxanthin (0'03 per cent), the total nitrogen 

 of the purin-bases amounting to 0'0456 per cent. Sarcolactic acid is 

 absent, but small amounts, O'Ol per cent, of fermentable lactic acid 

 were found. Potash salts preponderate over the sodium salts, and the 

 amount of sulphur is about 2*5 per cent, and therefore three times as 

 great as in vertebrae muscle. 



No other soluble albumins in addition to paramyosinogen (and 

 myosinogen) are found in the muscle substance proper, according to 

 v. Fiirth and Stewart and Sollmann ; the albumin which Kiihne once 

 described is a derivative of lymph, while the myoglobulin of Halli- 

 burton represents myosinogen which has escaped coagulation. 



Mays 5 has, however, found non-coagulating albumins in muscle, 



1 0. v. Fiirth, Zeitschr. f. physiol. Chem. 31. 338 (1900). 



2 H. Przibram, Hofmeisters Beitrdge, 2. 143 (1902). 



3 v. Fiirth, Zeitschr. f. physiol. Chem. 31. 338 (1900). 



4 M. Henze, ibid. 43. 477 (1905). 



5 K. Mays, Zeitschr. f. BioL 34. 268 (1896). 



