420 



CHEMISTRY OF THE PROTEIDS 



CHAP. 



The composition of the protamins Kossel has put into tabular 

 form : l 



The radicals of which protamins are built up may be as numerous 

 as they are in other albumins, but there is less variety and each kind 

 is repeated with great regularity in the different protamins. For this 

 reason it is possible to dissociate the protamins much more readily 

 into their dissociation -products than to dissociate other albumins. 

 Kossel believes the protamins to be the simplest albumins, and he has 

 placed them in the centre of his system. 



Protamins in their free state are difficult to prepare, but the 

 sulphates are comparatively easily obtained. Protamins have been 

 analysed directly and also after conversion into chlorides, which are 

 then precipitated from methyl-alcoholic solutions by means of platinum 

 chloride (Goto). Miescher was, however, the first to prepare the 

 platinum chloride double salt of salmin. 



The most recent analyses of Goto give these figures: 



1 A. Kossel, Berliner klinische Wochenschrift, No. 41, Oct. 1904, p. 1065. 



