442 



CHEMISTRY OF THE PROTEIDS 



CHAP. 



estimations of the dissociation -products are in most cases wanting. 

 According to Bang the pancreas-nucleic acid contains about 30 per 

 cent of pentose, and at least as much guanin. The pyrimidin- 

 derivatives seem to occur in smaller amounts. The constitutional 

 f ormulse of Bang l and Osborne and Harris 2 are, according to Cohnheim, 

 premature, but the author has thought it right to give Bang's views 

 on guanylic acid on p. 459. 



What is known regarding the percentage-composition of nucleic 

 acids is given in the following table of analysis : 



The authors calculate from these analyses the following minimal 

 formulae : 



C 40 H 52 N 14 25 P 4 (milt of salmon, Schmiedeberg 14 ). 

 C 40 H 56 N 14 26 P 4 (milt of salmon, Herlant 15 ). 

 C 40 H 54 N 14 27 P 4 (milt of herring, Mathews 5 ). 

 C 36 H 48 N 14 30 P 4 (yeast, Herlant 15 ). 

 C 40 H 54 (OH) 5 N 14 2V P 4 (yeast, Miescher and Schmiedeberg 3 ). 



1 J. Bang, Zeitschr. f. physiol Chem. 31. 411 (1900). 



2 T. B. Osborue and J. F. Harris, ibid. 36. 85 (1902). 



3 F. Miescher, "Milt of Salmon," in the posthumous papers edited by 0. Schmiede- 

 berg, Arch. f. experiment. Pathol. u. Pharm. 37- 1 (1896). 



A. Noll, Zeitschr. f. physiol. Chem. 25. 430 (1898). 



A. Mathews, ibid. 23. 399 (1897). 



J. Bang, ibid. 26. 133 (1898) ; 31. 411 (1900). 



L. Lilienfeld, ibid. 18. 473 (1893). 8 S. Kostytschew, ibid. 39. 545 (1903). 



J. Bang, ffofmeister's Beitrage, 4. 331 (1903). 



10 T. B. Osborne and J. F. Harris, Zeitschr. f. physiol. Chem. 36. 85 (1902). 



11 T. Araki, ibid. 38. 98 (1903). 



12 R. Altmann, Arch.f. (Anat. u.) Physiol. 1889, p. 524. 



13 F. Haiser, Monatsh. f. Chem. 16. 190 (1895). 



14 0. Schmiedeberg, Arch. f. experim. Path. u. Pharm. 43. 57 (1899). 



15 L. Herlant, ibid. 44. 148 (1900). 



