HEMOGLOBIN 



469 



The analyses in this table all refer to oxyhaemoglobin, with the 

 exception of the one by Otto, which represents methsemoglobin, but 

 the latter possesses the same composition as does oxyhaemoglobin. The 

 analyses show that haemoglobin is distinguished among albumins by 

 its high C- and N-percentage, and this explains its great heat value, 

 for the latter, according to Stohmann and Langbein, 13 amounts to 

 5885-1 cal. The dissociation-products of globin have already been 

 given on p. 70 ; the hsematin amounts, according to Schulz u and 

 Lawrow, 15 to between 4-4*5 per cent. See below, p. 508. 



The sulphur is partly in the form of cystin in the globin, while the 

 iron, is contained in the hsematin. 



Whether there are different kinds of haemoglobin Cohnheim believes 

 to be still undecided, but Gamgee 16 has pointed out that although 



1 F. Hoppe-Seyler, Zeitschr. f. physiol. Chem. 1. 121 (1877). 



2 G. Hiifner and Bucheler, ibid. 8. 358 (1884). 



3 J. C. Otto, Pftilgers Archivf. d. ges. Physiol. 31. 240 (1883). 



4 0. Zinnofsky, Zeitschr. f. physiol. Chem. 10. 16 (1885). 



5 M. Nencki, Schmiedeberg 's Archiv f. experiment. PcMwl. und Pharmak. 20. 332 

 (1885). 



6 F. N. Schulz, Zeitschr. f. physiol. Chem. 24. 449 (1898). 



7 F. Hoppe-Seyler, Med.-chem. Unters. p. 366 (1868). 



8 A. Jaquet, Zeitschr. f. physiol. Chem. 12. 285 (1888). 



9 C. v. Noorden, ibid. 4. 9 (1879). 



10 J. C. Otto, ibid. 7- 57 (1882). 



11 G. Hiifner, Arch. f. (Anat. u.) Physiol. 1894, p. 130. 



12 R. Gscheidlen, Pfliigers Archivf. d. ges. Physiol. 16. 421 (1878). 



13 F. Stohmann and H. Langbein, Journ. f. prakt. Chem. [2] 44. 336 (1891). 



14 F. N. Schulz, Zeitschr. f. physiol. Chem. 24. 449 (1898). 



15 D. Lawrow, ibid. 26. 343 (1898). 



16 A. Gamgee, Schafer's Textbook of Physiol. 1. 204 (1898). 



