x H^MATINIC ACIDS 511 



which is probably identical with methylpropylpyrrol, although it may 

 perhaps be butylpyrrol : 



CH 3 . C C CH 2 . CH 2 . CH 8 HC C CH . CH 2 . CH 3 



HC CH HC 



NH NH 



3-methyl 4-w-propylpyrrol. Butylpyrrol. 



According to an abstract by Czapek 1 in the Zentralbl. f. Physiologic, 

 Kiister 2 believes that in haematoporphyrin and in phylloporphyrin 

 there is not found a normal indolring, but an iso-indolring : 



N 



Normal indolring. Iso-indolring. 



Haematinic Acids 



By oxidising hsematin dissolved in glacial acetic acid with a watery 

 solution of sodium bichromate at the temperature of the water bath, 

 Kiister 3 obtained two ether-soluble acids, which crystallised readily 

 and which he called hsematinic acids : 



Anhydride of tribasic hsematinic acid C 8 H 8 5 . 



Dibasic hsematinic acid C 8 H 9 N0 4 . 



These acids are formed, according to Kiister, 4 Nencki and Zaleski, 5 by 

 the oxidation of methylpropylpyrrol or hsemopyrrol, thus : 



. CH 2 . CH 2 . CH 3 CH 3 . C == C. CH 2 . CH . COOH 

 O.C 



NH NH 



Methylpropylpyrrol. Dibasic hsematinic acid. 



*' Czapek, Zentralbl. f. Physiol. 18. 591 (1904). 



2 W. Kiister, Ber. d. deutsch. bot. Ges. 22. 339 (1904). 



3 W. Kiister, Zeitschr. f. physiol Ghem. 28. 1 (1899) ; 29. 185 (1900). 



4 W. Kiister, Berichte d. deutsch. chem. Gesellschaft, 35. III. 2948 (1902). 



5 M. Nencki and J. Zaleski, ibid. 34. I. 997 (1901) ; J. Zaleski, Zeitschr. f. physiol. 

 Chem. 37. 54 (1902). 



