FATE OP TUBERCLE ! \< 11.1.1 OTTSIDK THK ANIMAL BODY 303 



TAHI,K (>. -Continued 



Author 



Kirstein 511 

 (continued) 



Park and 



Williams 11 



Twitchell 1 



Sormani 138 

 L<eNoir and 

 Camus 86 



Rodet and 120 

 Delanoe 



Kohlisch' 



Pair 



1905 

 1905 



1906 

 1907 



1907 



1908 



Conditions 



Books and papers 



Sputum dust 



Cloth ravelings 



Street dust 



Dried tuberculous sputum gradually 

 loses its virulence, but still infective 

 Tuberculous sputum: 



In paraffined bottles in dark moist 

 box 



In paraffined bottles in diffuse light 



In paraffined bottles in thermostat. 



In cotton-stoppered bottles in dark 

 moist box 



In cotton-stoppered bottles in dark 

 closet 



On ice 



Tuberculous sputum: 



On handkerchiefs 



On towels 



On carpets 



In sand in moist light place 



In sand in dry light place. .' 



In open bottles, out doors, winter . . 

 Dried tuberculous excretion at 35 C. 

 I^arge quantities of air were aspirated 

 from tuberculous hospitals and the 

 dust injected under the skin of 

 guinea pigs. From 4 tests aspi- 

 rating respectively 270, 2000, 20000 

 and 53000 liters, in no case were 



tubercle bacilli found 



Eleven samples of dust from local 

 offices and private dwellings were 

 inoculated into guinea pigs, with 



wholly negative results 



Fresh tuberculous sputum or a pure 

 culture of tubercle bacilli was inti- 

 mately mixed with dust obtained 

 from dwellings and factories, and 

 the number of tubercle bacilli that 

 a guinea pig inhales in a given 

 time was determined. It was 

 found that tuberculosis was pro- 

 duced in the test animals when as 

 low as 50 tubercle bacilli were in- 

 haled, and that the inhalation of 

 270 or more of these germs al- 

 ways produced tuberculosis. An- 

 other series of experiments were 

 made with dust from 15 dwellings 

 where consumptives were living. 

 The rooms were small and poorly 

 kept. Eighteen guinea pigs 

 breathed for some time in dense 

 clouds of this dust. None of these 

 guinea pigs became tuberculous. 



Not killed | Killed 



8 days 



4 days 



5 days 

 3 days 



2 to 3 mo. 



170 days 



124 days 



33 days 



157 days 



100 days 

 102 days 



70 days 



70 



39 

 123 



30 

 110 



15 days 



14 days 



7 days 

 10 days 



8 days 



188 days 

 175 days 

 100 days 



172 days 



141 days 

 153 days 



110 days 

 110 



70 

 148 



70 

 132 



all 



11 samples 



