Timothy Richards Lewis, M.B. xxv 



Cholera-Discharges ; " and, in the same way, most of their subsequent work on this and 

 kindred subjects from time to time appeared, such as "Bladder Worms found in Beef and 

 Pork," by T. K. Lewis ; " Cholera in Madras,"' by D. D. Cunningham ; " A First Series of 

 Microscopical and Physiological Observations on Cholera" (1872) ; a second series (1874) ; 

 " Soil in Eelation to Disease ; " and many other reports of a similar character. 



During intervals of cessation from cholera investigation, Lewis occupied himself 

 with other important pathological inquiries. In March 1870, when examining a specimen 

 of milky urine in Calcutta, he found that it contained numerous microscopic nematoid 

 worms in a living condition, which he described and figured in a report published in 1870 

 by the Indian Government, an abstract of which also appeared in the British Medical 

 Journal of November 19th, 1870 ; and specimens were forwarded to the late Dr. Parkes, 

 at Netley. Towards the beginning of July 1872, Dr. Lewis found nine minute nematoid 

 worms in a state of great activity on a slide containing a drop of blood from the finger 

 of a Hindoo suffering from chyluria. These were identical in character with those pre- 

 viously found in the urine, and furnished the first recorded instance of nematoid haema- 

 tozoa having been found in man. Since that time, he continued to make many similar 

 observations, and traced this helminth (the Filaria sanguinis hominis) to the blood 

 direct, and to one or other of the various tissues and secretions of the body of numerous 

 patients, all of whom were known to suffer, or to have suffered, from chyluria, or some 

 closely allied pathological condition, — observations which have since been confirmed by 

 other observers in numerous instances. These observations were published in the Eighth 

 Annual Report of the Sanitary Commissioner with the Government of India, and also in 

 the Indian Annals of Medical Science, vol. xvi., " On a Hsematozoon in Human Blood ; its 

 Connection with Chyluria and other Diseases " ; another paper was published in 1874, in 

 the same periodical, " On the Pathological Significance of Nematode Hsematozoa " ; and, 

 lastly, in Quain's Dictionary of Medicine, under the article " Chyluria," Dr. Lewis gave a 

 full and masterly account of what is known of this disease in the various countries in 

 which it has been found. Some time after he had written the article for the Dictionary, 

 he succeeded in obtaining what is, beyond question, the mature form of this helminth. 

 On August 7th, 1877, at the hospital of the Calcutta Medical College, two living speci- 

 mens (a male and a female) were found in the body of a young Bengalee, who was 

 affected with well marked nsevoid elephantiasis of the scrotum (elephantiasis lymph- 

 angiectodes), associated with the presence of embryo filaria in the blood. 



Dr. Lewis began to investigate leprosy in 1873, and in 1877 published, conjointly 

 with D. D. Cunningham, a report on Leprosy in India ; and in the same year they also 

 published a report on The Oriental Sore. In this year he was elected a Fellow of the 

 Calcutta L^niversity. 



In 1878 he published Microscopic Organisms found in the Blood of Man and 

 Animals ; and in the same year, conjointly with D. D. Cunningham, a most valuable 

 monograph on Cholera in Relation to Certain Physical Phenomena. During this period 

 Lewis was directing much attention to the question of soil in relation to disease; and, in 



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