viii Table of Contents. 



PAGES 



C. Ohsfrvations on the blood as to the existence of monads, bacteria, fungi, and of sarcince in 

 it.- — ^Healthy human blood contrasted with cholera blood — Eesults of the introduction of putrefying 

 matter into blood. 



II. Experiments on the Inteodttction op Organic Fluids into the System. 



A. Injection of choleraic and other organic fluids into the veins of animals. — (1) Experiments 

 with choleraic material used fresh, and with material from one to twenty-two days old — 

 Oscillatoria-like vibriones on mucous surface of small intestines, and in mesenteric glands — 

 Distomata found in bile ducts of dogs — (2) Injections of aqueous solutions of choleraic material in 

 the veins of animals — (a) Freshly prepared solutions — (ft) Prepared 24 hours before use — (c) 48 

 hours before use — (3) Injections of organic solutions, other than of a choleraic nature, into the 

 veins of animals — (a) Injected while fresh — (ft) Injected when one day old — (c) When two days 

 old — (rZ) When three days old — {e^ When four days old — (/) When five days old — (17) When 

 seven days old. 



B. JExperiments on the iyitroduction of choleraic and of other 07'ganic solutions iJito the 

 peritoneal eavity of animals.— ^&ect% of injecting a decomposing choleraic evacuation — Effects 

 of injecting red serous and sero-sanguinent peritoneal fluid — Of injecting solution of healthy 

 evacuation. 



C. Analysis of the series of experiments. — General summary of results. 



III. Experiments on Section of Splanchnic and Mesenteric Nerves. 



A. Section of the splanchnic nerves. — Details of experiments. 



B. Effects of section of mesenteric nerves. — Details of experiments — ^Certain points established 



by the experiments 65 — 141 



A Report on Microscopical and Physiological Researches into the Nature of the 

 Agent or Agents producing Cholera (Second Series). By Drs. Lewis and D, D. 

 Cunningham. 1874. 



I. Microscopic Examinations of Blood. — Reason for further examinations — Methods of 

 research — Nature of observations — Wax cells. 



A. The blood in health. — Echinulation of red corpuscles — Produced by pressure, etc. — 

 Molecular matter of disintegrated white corpuscles — Nature of motile particles — Evanescent 

 character of fibrinous threads — Absence of bacteria — Absence of fungi — " Spectral bacteria " — 

 Milky spots — How to distinguish them from solid bodies — " Zone immobile " — Sarcinae. 



B. The blood in cholera. — Condition of the red corpuscles — A typical specimen — No 

 characteristic organisms visible. — Tables I to III. 



C. The blood in diseases other than cholera. — Vaccinia — Leucocytes not numerous — Motile 

 particles — Absence of bacteria — Syjyhilis : Absence of foreign organisms in — Conditions under 

 which organisms were observed in blood — Tables IV to X — Bacteria and j^ost-mortein changes — 

 Temperature and the development of bacteria — Organisms developed in the tissues of healthy 

 animals shortly after death — Organisms in the blood of dying animals — Post-mortem development 

 of organisms in the glands, etc. — Illustrative cases — " Mycosis intestinalis " — Pathological signifi- 

 cance of vegetable organisms in the tissues after death — The genera to which these organisms 

 belong — Bacteridia — Microzymes — Relation of bacteria to disease — Significance of the presence 

 of organisms in the tissues — Leucocytosis incompatible with the development of bacteria — 

 Bacteria as a result of ante-mortem- changes — Multiplication of disease-poisons. — Table XI. 



II. Experiments on the Introduction op Choleraic and other Organic Fluids 

 into the System. — Experiments on small animals liable to mislead — Reference to Thiersch's 

 experiments at the Vienna Conference — Number of observations on which our conclusions are based. 



A. Experhnents on the injection of choleraic and other organic fluids into the veins of 

 animals. — Introductory remarks — (1) Remit of introducing normal alvine di,<icharges into the 

 circulation: Percentage of results — Varying susceptibility of animals to septic influences —Tables 

 XII to XV — Effects of heat on the properties of the solutions — (2) Experiments on the intro- 

 duction of Choleraic alvine discharges into the circulation : Difference in degree between the toxic 

 properties of fresh choleraic and normal excreta — Influence of heat (Table XVJ)— Percentage 



