PART I.] Observations Regarding Fettenkofer s Theory of Cholera. 41 



2. That cysts or " sporangia " of fungi are but very rarely found under any 

 circumstances in alvine discharges ; 



3. That no special fungus has been developed in cholera stools, the fungus 

 described by Hallier being certainly not confined to such stools ; 



4. That the still and active conditions of the observed animalculse are not 

 peculiar to this disease, but may be developed in nitrogenous material even outside 

 the body; 



5. That the flakes and corpuscles in rice-water stools do not consist of epithelium, 

 nor of its debris, but that their formation appears to depend upon the effusion of blood- 

 plasma ; and that the " peculiar bodies " of Parkes found therewith correspond very 

 closely in their microscopic and chemical characters, as well as in their manifestations 

 of vitality, to the corpuscles which are known to form in such fluid ; these are generally, 

 to a greater or less degree, associated with blood-cells, even when the ] presence of such is 

 not suspected, especially as the disease tends towards a fatal termination, when the 

 latter have been frequently seen to replace the former altogether ; and 



6. That no sufficient evidence exists for considering that vibriones, and suchlike 

 organisms, prevail to a greater extent in the discharges from persons affected with cholera, 

 than in the discharges of other persons, diseased or healthy ; but that the vibriones, 

 bacteria, and monads (micrococcus) may not be peculiar in their nature, for these do 

 vary, may not be the product of a peculiar combination of circumstances, and able to 

 give origin to peculiar phenomena in a predisposed person, is " not proven," 



In bringing this part of the report to a close, I wish to express my sincere thanks to 

 Dr. John Murray, Inspector Greneral of Hospitals, Indian Medical Department, who has, 

 week by week, watched the progress of these experiments, and given such practical advice 

 and assistance as his long study of the subject particularly enables him to do. I also 

 desire to tender my thanks to Dr. Brougham of the Presidency Greneral Hospital, 

 and to Dr. Baillie of the Chandney Hospital for the facilities which were placed at 

 my disposal for obtaining the materiel requisite for these examinations ; as well as to 

 Dr. Norman Chevers, Principal of the Medical College, for permission to make use of 

 his private library, as well as the library attached to the College. 



II. REMARKS REGARDING THE SOIL, ETC., OF CERTAIN PLACES IN RELATION 

 TO FETTENKOFER' S THEORY OF THE CONNECTION OF CHOLERA WITH THE 

 VARIATION IN THE LEVEL OF THE SUBSOIL WATER. 



Seeing that Professor Pettenkofer's observations extend over a period of sixteen years, 

 during which constant observations have been taken by him of the water-level in 

 various parts of Munich and elsewhere, it will be at once evident that the short period 

 which has' elapsed since the commencement of this investigation in India cannot 



