96 Researches Regarding Cholera : The Blood. [part i. 



bladder contained bile. The spleen and kidneys were healthy. On opening the thorax, 

 the pleural cavities were found to be free of fluid, and the membranes appeared to 

 be perfectly healthy. The lungs were collapsed, airless, and containing very little 

 blood. The pericardium was slightly injected. The right cavities were distended with 

 fluid blood, and the left side also contained a little blood. 



Preparations of the blood were procured, and whether under common covering 

 glasses, or in hermetically sealed wax-cells, were found to be swarming with very active 

 bacteria after the lapse of twelve hours. 



Experiment XVII. — A large healthy pariah dog was put under chloroform at 

 5 P.M. of the same day in which the preceding experiment was performed, and half 

 an ounce of the same fluid employed in it injected into the right median vein. The 

 operation was rapidly and successfully performed, and the animal quickly revived ; but 

 it appeared to be in a condition of profound collapse while under observation, and 

 died during the course of the night, having passed some liquid mucous evacuations 

 of a pink colour during the interval. The evacuations passed immediately after the 

 operations were natural in colour and consistence. 



A post-mortem examination was performed at 7 a.m., 14 hours after the injection 

 took place. Rigor mortis was strongly marked. Pinkish fluid* ran from the nose 

 and mouth when the body was lifted. There was no evidence of peritonitis, and the 

 external surface of the intestines was very pale, as in the preceding case. The stomach 

 contained a little pale pinkish mucus ; but the membrane beneath was not congested. 

 The duodenum contained more abundant and more highly coloured semi-fluid mucous 

 matter, and the mucous membrane throughout the rest of the small intestines was 

 softened, and coated with similar material. There were also small spots of extravasation 

 throughout. The large intestine was not aflfected. 



The mesenteric glands were all intensely congested and full of pinkish fluid 

 closely resembling the intestinal material. The latter was found on microscopic exami- 

 nation to be composed of cylindrical epithelium mixed with abundance of bacteria 

 and vibriones. The liver was variagated with light, yellowish fatty spots. It contained 

 no evidences of embolism. The kidneys and spleen were perfectly healthy. The 

 bladder was empty. The pleural cavities were healthy, and the lungs were collapsed, 

 pale and devoid of any traces of embolism. The pericardium was quite healthy. The 

 right cavities of the heart were empty, and the left contained a little fluid blood. 

 Preparations of blood were procured from the heart and from one of the systemic 

 veins. These, when examined a quarter of an hour subsequently, showed no active 

 bacteria, but a uniform sprinkling of minute motionless particles throughout the 



* The fluid consisted of mucus containing innumerable ova and a few perfect specimens male and female, of 

 Pentastoma twn'wules. 



