PART I.] Experiments on a Large Dog and Small Pup. loi 



of chloroform, and half an ounce of choleraic fluid was injected into the right 

 femoral vein. 



The fluid was the same as that employed in Experiments XVI, XVII, and 

 XVIII, but had now been kept for 15 days. It retained its intensely foetid odour, 

 but its re-action was now faintly acid. The animal rapidly recovered from the 

 influence of the chloroform, appeared totally unaffected by the operation, and 

 remained in perfect health for the next three days, when it was made the subject 

 of an experiment on the effects of section of intestinal nerves. 



Experiment XXVIII. — A large healthy pariah dog having been put under the 

 influence of chloroform, three drachms of the same fluid employed in the preceding 

 operation which had just been performed, were injected into the left femoral vein. 



The dog appeared entirely unaffected by the operation, and remained quite 

 healthy for the next three days, at the close of which period it was killed under the 

 influence of chloroform. 



An immediate post-Tnortem examination was made, and the intestines, together 

 with the other thoracic and abdominal viscera, were found to be. perfectly healthy in 

 appearance. Some of the mesenteric glands were reserved as in Experiment XI, and 

 were examined after 24 hours. The fluid contained in the interior of them showed 

 an abundance of moving molecular matter, but not a single specimen of the elongated 

 vibriones occurring in the other reserved glands. 



Experiment XXIX. — A small pup, similar to those employed in Experiments XXIV 

 and XXV, was put under chloroform, and one drachm of the evacuation employed 

 in Experiment XX, etc., was injected into the right femoral vein. The operation 

 was completed with perfect success and with no haemorrhage or disturbance of the 

 surrounding tissues. Shortly after the injection respiration ceased but was readily 

 re-established. 



After the completion of the operation the respiration was considerably disturbed. 

 In the course of an hour or so, the animal began to whine and appeared to be in 

 pain, moving about his limbs and turning on his back. He vomited three or four 

 times and passed one evacuation. He died 4 hours after the operation, and a 

 post-moi'tem examination was performed 2^ hours after death. 



Rigor mortis was strongly marked. The body was scarcely warm, and the 

 wound was quite healthy. The peritoneal cavity contained no fluid, and the membrane 

 was not injected. The intestines were distended, and. in greater part, of a purplish 

 hue. They contained a pinkish, slimy substance, which, as a rule, was most highly 

 coloured opposite the most purplish portions of the intestine. The pinkish tint of 

 the contents did not, in this instance, correspond with the presence of patches of 

 worms, for the latter were in several instances observed to occupy pale portions of 

 the intestine. The liver was healthy ; the kidneys were congested. 



