io6 Researches Regarding Cholera: The Blood. [part 



3. — Injections of organic solutions, other than of choleraic nature, into the 



veins of animals. 



The arrangement adopted in the preceding sections will be followed out in this 

 also, so that comparisons between the various classes of experiments may be more 

 readily made. The introductory remarks which have been made concerning them, 

 apply equally to this, the conditions under which they were conducted being the 

 same ; the animals were taken indiscriminately, irrespective of sex, age or strength, 

 the solutions for injection having usually been prepared before the animals had been 

 seen. 



It will be seen that the femoral and brachial veins have been selected in 

 preference to the veins of the neck, owing to the complications which we had, 

 in early attempts, frequently observed to have followed the occurrence of even slight 

 cellulitis in that region. 



(«) — The injecting material used while fresh. 



Experiment XLI. — A small quantity of recently drawn fowl's blood was shaken 

 up with about its equal weight of water, and filtered ; half an ounce of this filtered 

 mixture was then injected into the right femoral vein of a young dog four months 

 old, whilst under the influence of chloroform. 



In a short time the animal recovered from the effects of the anaesthetic, and 

 soon partook of food. vS light lameness alone indicated that anything had occurred, 

 and on the third day he appeared quite well, when he was subjected to a repetition of 

 the experiment (vide Exp. XLIX). There were no traces of blood corpuscles in the 

 filtered solution used for injecting. 



Experiment XLII. — Some freshly-drawn fowl's blood was prepared, as in the 

 foregoing, but not filtered, so that coagula and corpuscles were sucked up into the 

 syringe, it having been ascertained that corpuscles, as well as coagula, were retained 

 when an attempt was made to strain off the latter through tow. The nozzle was 

 introduced as before into the femoral vein of a powerful dog, and three fluid drachms 

 injected into it. 



The dog after recovering from the chloroform did not appear to be much affected 

 by the operation, and three days afterwards looked so well that he was again placed 

 on the table in order to introduce some putrefying blood, but respiration suddenly 

 stopped, and could not be re-established. The internal organs were perfectly healthy, 

 not the slightest evidence of embolism being manifested. 



Experiment XLIII. — Three drachms of a watery solution of recently passed 

 healthy foecal matter, which had been five times filtered through muslin (so as to 



