io8 Researches Regarding Cholera : The Blood. [part i. 



not fluid, and towards the ileo-coecal valve the surface was quite pale. The large 

 intestine was pink and contained pinkish mucus. 



There was a yellow patch at the edge of one of the lobes of the liver in 

 which the minute vessels of the part presented a prominent tortuous appearance, 

 evidently due to small local congestions. The spleen was large, and showed 

 numerous soft milky nodules on section. The kidneys were normal, not congested. 

 The lungs healthy, collapsed and scarcely crepitant ; the right cavities of the heart 

 were full, the left empty. 



Experiment XLVI. — A little ordinary foecal matter was diluted with about twice 

 its weight of water, allowed to stand for twenty hours, and afterwards twice strained 

 through three layers of muslin. The solution was then injected into the left femoral 

 vein of a young dog whilst under the influence of chloroform. During the operation, 

 the respiratory movements suddenly ceased, but were re-established after artificial 

 respiration had been persevered in for nearly ten minutes. 



The animal seemed to be quite comfortable during the day, but at night he 

 became sluggish, passed reddish, liquid stools, and died on the following day, twenty- 

 nine hours after the operation. 



The body was examined an hour and a half after death. There were no signs 

 of peritonitis. The stomach was empty, the duodenum contained yellowish, bile-stained 

 fluid, and both small and large intestines contained a considerable amount of a 

 grumous substance of the consistency and colour of black-currant jam or prune-juice, 

 evidently due to altered blood exudation. The liver was extremely fatty. Kidneys 

 and spleen normal. The heart was healthy, the cavities on both sides empty. There 

 were numerous pneumonic patches interspersed throughout the lungs, but no indication 

 of further mischief. 



Experiment XLVII. — The dog used in Exp. LIX having quite recovered was put 

 under chloroform again, and six drachms of a solution of normal evacuation, prepared 

 twenty -four hours previously, were injected into the left femoral vein. The animal 

 did not seem to be the least affected by this operation neither until the next day, 

 when it became sickly, and still more so on the second day, when chloroform was 

 again administered, and a poat-'morte'rti examination at once made. 



There was no fluid in the peritoneum, nor the least trace of peritonitis ; the 

 intestinal mucous membrane appeared to be perfectly healthy and pale, so were the 

 mesenteric glands, and all the other abdominal and thoracic organs. 



A wax-cell preparation of the blood from the vena cava was made, and examined 

 the next morning, when a scanty sprinkling of active bacteria were seen to be present ; 

 and on the third day the preparation was crowded with stiff short bacteroid bodies, 

 perfectly still and resembling crystals. 



