PART I.] Injections of Organic Solutions, not Choleraic, into Veins. 109 



Experiment XLVIII. — A very powerful pariah dog was put under chloroform, and 

 six drachms of fluid which had been employed in the preceding experiment, ten hours 

 previously, were injected into the right femoral vein. 



The animal quickly recovered, and was under observation for three days, but not 

 the slightest indications of functional disturbance were manifested, and it was subjected 

 to another operation {vide Exp. LXTI). 



(c) — The organic material injected being two days old. 



Experiment XLIX. — A small quantity of the solution of blood which had remained 

 over since its employment in Exp. XLII of this series, and which was found to be 

 in an advanced stage of decomposition, swarming with bacteria, was filtered as before, 

 so that all solid particles together with the bacteria were got rid of, and afterwards 

 injected into a branch of the left femoral vein of the same dog, into whose right 

 femoral vein the fresh filtered solution had previously been injected, without ill effects 

 (vide Exp. XLI). 



The animal was under observation for four days, was in no way affected, eating 

 freely any food that was placed before him. 



Experiment L. — Four drachms of a decomposing solution of ordinary foecal matter 

 were injected into the right femoral vein of a medium-sized dog. No blood was 

 lost, and but very little chloroform used, still the animal almost immediately after 

 the operation began to breathe in an intermittent manner, gasped several times and 

 died. 



The body was examined immediately, in order to ascertain whether the bacteria 

 which the solution contained, had passed through the lungs into the left side of the 

 heart. Specimens of blood were, therefore, carefully removed from the right and 

 from the left cavities, and on microscopic examination, we found numerous very 

 energetic bacteria in all the specimens. The preparations of blood from the right 

 side of the heart appeared to contain more bacteria than those from the left. All 

 the organs were healthy, no indications existing of the cause of the sudden death. 



Experiment LI. — A large healthy pariah dog was put under chloroform as usual, 

 and six drachms of the solution of ordinary alvine discharge used in Exp. XLVII, 

 but now forty-eight hours old, were injected into the left femoral vein. The ligature 

 commanding the lower end of the vein unfortunately slipped, and considerable 

 haemorrhage ensued. It was, however, ultimately secured, and when the animal awoke 

 it ran away. 



Having been re-caught, it was kept under observation during the day, but nothing 

 special was noted. During the night, however, the animal died, and a post-mortem 

 examination was made next morning. The intestines were filled with a soft pinkish 

 substance, consisting chiefly of epithelium, and the mucous surface of the small 



