I20 Researches Regarding Cholera. [fart i. 



after it, showed no symptoms of pain, and in the afternoon ran home along with the 

 servant, who had the charge of the dogs, to his hut in a village, about half a mile off. 

 On the following morning he was brought back, and at this time also appeared in no 

 way affected by the operation. Chloroform was- administered until respiration ceased, 

 and a jpost-mortem examination was then immediately performed, nearly 24 hours 

 after the injection had taken place. 



On opening the abdomen about three ounces of pinkish-grey fluid were found in 

 the peritoneal cavity. The mesentery was thickened and injected, and there were a 

 few small patches of soft lymph on the liver. The walls of the intestines appeared to 

 be slightly thickened, but they were otherwise normal in appearance. The bladder 

 was distended with fluid. The rest of the abdominal and thoracic viscera appeared 

 to be quite healthy. 



Experiment LXXI. — A strong healthy pariah dog was put under the influence 

 of chloroform at 8 a.m., and half an ounce of a solution of a normal evacuation was 

 injected into the peritoneal cavity. The solution had been prepared three days 

 previously, and was in an active state of decomposition. 



The dog was kept under close observation for seven hours, during which it showed 

 no marked symptoms of any kind, and then went home with the man in charge, 

 walking along with him without manifesting any symptoms of pain or inconvenience. 

 The man brought its body next morning, and stated that, soon after he took it to his 

 house, it suffered from severe rigors, and that it died about eight hours afterwards 

 without having shown any other decided symptoms. 



There was no vomiting, and no evacuations were passed subsequent to the 

 operation. A post-Tnortem examination was performed eight hours after the occurrence 

 of death. 



On opening the abdomen, extensive signs of peritonitis presented themselves. 

 The cavity contained an abundance of fluid of a reddish tint and somewhat thick con- 

 sistence. When subjected to microscopic examination, it was found to contain a few 

 red blood-corpuscles, and very numerous granular pyoid cells of a more or less circular 

 form. They were all perfectly motionless, seemingly dead, and the fluid surrounding 

 them was crowded with active bacteria and vibriones. 



The interior of the small intestines presented the appearances previously described 

 in Experiments I.(XVIII and LXIX. There was a continuous coating of a dark tarry 

 aspect beneath which the epithelial surface appeared quite healthy. As before, about 

 six inches of the ileum, immediately above the ileo-ccecal valve, was unaffected. The 

 large intestine also was covered with a coating of tarry material. 



No other noteworthy lesion was to be found in any of the abdominal or thoracic 

 organs. There was no pleurisy. 



Specimens of blood from the right ventricle were found to contain a few bacteria 

 when subjected to oareful examination under a i^th. immersion lens. 



