140 Researches Regarding Cholera. [part i 



membrane being moist and covered with a layer of soft mucus of a sanguineous hue. 

 The interior of the second loop (6) was also empty, but the mucous membrane was in 

 this case dry and much less congested than that of the portions of intestine on either 

 side of the ligatures. 



The congested state of the mucous membrane' was probably due to the fact that 

 a considerable amount of peritonitis had been caused by the operation. 



Experiment IX {No. 12). — A large healthy pariah dog was put under the 

 influence of choloroform, and the two nerve loops of the small intestine were divided 

 in the usual way. Into one loop (a) an ounce of water was injected, whilst the other 

 (6) was left empty. 



Nine hours afterwards the animal was killed, and a jpoat-moTte'm examination was 

 performed at once. 



The former loop of intestine (a) was empty, and contained merely a little 

 sanguineous mucus, but the latter {h) was fully distended with clear serous fluid, 

 containing a few small pale yellowish flocculi. The mucous membrane was soft and 

 of a macerated aspect. 



No mistake could have been made as to the identity of the two loops, as they 

 had been carefully distinguished by means of different ligatures, both ends being cut 

 short in one case, whilst one end was left uncut in the other. The flocculi contained 

 in the serous fluid were examined microscopically, and were found to consist of a 

 molecular basis crowded with bioplasts of all sizes, and exactly resembling the flocculi 

 occurring in choleraic dejecta. 



Careful dissections of the nerves were made in both cases. In neither were 

 they entirely divided, but the remaining nervous connections were decidedly greater 

 in the second loop (6) than in the first (a). 



Experiment X (No. 15). — A large healthy pariah dog was put under the 

 influence of chloroform, and the nerves of a loop of intestine were divided in the 

 usual way. The animal was killed 9f hours afterwards, and a post-moi'tem exami- 

 nation was performed at once. 



The central loop of intestine contained brownish fluid. The mucous membrane of 

 the two lateral loops was very dry, and was coated with a layer of brownish material 

 identical in colour, and probably in nature with that dissolved in the fluid in the 

 central loop, of which the nerves had been divided. A careful dissection was made 

 of the nerves, and it appeared that, whilst the main trunks had been freely 

 divided, one or two lateral connecting loops of some size remained intact. 



The last two cases are peculiarly instructive and noteworthy, inasmuch as they 

 appear to demonstrate a fact which had never previously been experimentally 

 determined, namely, that the relation which the secretion of the small intestines 

 bears to their nervous supply is strictly analogous to that which has long been known 



