PART I.] 



Experiments with Fresh Choleraic Excreta. 



^11> 



TABLE XVI. 



(6) — The, Gholefraic material introduced being Fresh, hut subjected to Heat. 



Experiment 



No. 



XXXVII 



XXXVIII 



XXXIX 



XL 



XLI 



XLII 



XLIII 



XLIV 



XLV 



XLVI 



XL VII 



XLVI II 



XLIX 



Vein selected. 



Femoral. Saphena. 



Temperature. 



Drachms | 



Degree. ;^iiiut,es' injected. 

 ^ duration. 



Total... l.S 



212° 



212° 

 212° 

 212° 

 212° 



212° 



212° 



212° 



212° 



212° 



212° 

 212° 

 212° 



Three 



Four 

 Three 

 Three 

 Three 



Three 



Three 



Three 



Three 



Affected. 



Six 



Four 

 Four 

 Seven 

 Four 



Six 



Four 



Eight 



Eight 



Three 



Three 

 Three 

 Three 



Four 



Four 

 Four 

 Four 



The dog died within 8 hours, and the 

 jiosit-mortcvi wa=5 conducted H hour 

 later. Intestines coated with soft 

 gelatinous pinkish material, and the 

 mucous membrane affected. Reddish 

 serous-fluid in the pericardium. 



The same fluid used as in the last. 



The same fluid was injected unboiled 

 without result in Exp. XXX, Table IV. 



Death within 6 hours after considerable 

 purging. The small intestines con- 

 tained watery fluid and numerous 

 whitish flofculi. The mucous surface 

 coated with a creamy layer, beneath 

 which it was found to be extremely 

 congested, and in some parts disin- 

 tegi-ated. The large intestine also 

 contained fluid. 



This animal was treated in precisely the 

 same manner as the last, with the 

 same fluid and at the same time. 

 Death took place here also within 6 

 hours. The symptoms ha<l been the 

 same, and the jxi.s't-inortnn appear- 

 ances also, except that there was less 

 watery fluid in the intestine. 



The animal was killed on the second day. 

 There had been no very marked symp- 

 toms of illness, nor were there any 

 marked lesions observed at the posf- 

 niortcm examination, except that the 

 last two feet of the small intestine 

 had evidently been materially affected. 



Died within 5 houi-s after having passed 

 copious fluid stools and manifested 

 symptoms of considerable i)ain. The 

 matei-ial used was the same that was 

 employed in the last experiment, as 

 also in Exp. XXXIII, Table IV, but 

 in the latter case unboiled and with 

 a negative result. A jwst-moj'tem ex- 

 amination was made immediately after 

 death. The intestines were full of 

 watery and slimy fluid. The venous 

 blood was very dark : no bacteria 

 could be detected in it. 



Died within 12 hours. No very marked 

 post-mortem lesion, the principal being 

 peritonitis. 



Died within 15 hours. 



Unaffected. 



Not much affected. 



The fluid injected in the last four expe- 

 riments was derived from the same 

 patient, a well-marked case of cholera ; 

 and counter-experiments were made 

 with it, without boiling, in three other 

 dogs, two of which yielded no results. 

 (Mtfr Exp. XXXIV— XXXVI. Table 

 XV.) 



