178 



Researches Regarding Cholera : the Blood. 



[part I. 



of iron) was employed ; and in the remaining twenty-four a solution of various 

 excrementitious substances — a little tincture of iodine being added to the latter in 

 two instances. Out of the eleven experiments just referred to, inflammatory exudation 

 was obtained from seven ; and from the other group of twenty-four experiments, a 

 similar fluid was obtained in fourteen. It will therefore be seen that the results were 

 positive in twenty-one out of thirty-five cases, or at the rate of 60 per cent. 



The following table will show the effect of transferring the morbid exudation thus 

 obtained — whether injected when perfectly fresh, after a delay of twenty-four hours, 

 or after being subjected to heat: — 



TABLE XVIII. 



Showing the result of injecting solutions of Inflammatory Products into the 

 Peritoneal Cavity of Animals. 



10 

 11 



12 

 13 

 14 



Re M A B K s. 



The fluid used in this experiment had been obtained from the 

 peritoneal cavity of a dog in which peritonitis had been induced 

 by the injection into its peritoneum of about an ounce of the 

 watery contents of the small intestine of a man who hatl died 

 of cholera. The second dog was in no way affected by the 

 operation. 



The fluid introduced in this instance was diluted, purulent matter, 

 which had been obtained from an abscess which had formed in 

 the subcutaneous tissue of the same dog. 



Intense inflammation of peritoneum, pleura, and pericardium : 

 death had occurred within 12 hours. The fluid originally in- 

 jected had been obtained from the peritoneal cavity of a dog, 

 in which peritonitis had been produced by the introduction of a 

 solution of normal alvine discharge 24 hours old. 



Death within 6 hours. The fluid which brought this about had 

 been obtained from the dog in Exp. 8. Consequently, it was 

 the third removed from the original irritant. The poxt-mortein 

 appearances were the same as in the last. 



Death within 5 hours. The fluid in this case was the fourth 

 removed, having been obtained from the dog used in Exp. 9. 



Unfortunately our supply of animals ceased for a couple of days, 

 so that we were unable to carry this series any further. 



Peritonitis, pleurisy, and pericarditis, with sanguineous fluid in 

 the pericardial sac. The primary inflammation bad been in- 

 duced by means of a solution of normal alvine discharge intro- 

 duced into the peritoneum of another dog two days previously. 



The fluid used had been obtained from the dog in Exp. 11, and 

 was consequently the second removed. 



No effect beyond slight congestion of the peritoneum. The fluid 

 injected had been strained subsequent to boiling. 



The same fluid used as in the last, but it was not strained subse- 

 quent to boiling. 



