PART II.] Description of the Pale or Ochroid Variety of the Disease. 347 



The oily matter was throughout generally more or less fluid, but in some places both 

 in the bones and soft tissues there was an abundance of distinct small glistening 

 particles, of a white colour and composed of dense radiating masses of acicular fat 

 crystals. Nowhere was there the slightest indication of the presence of any brown or 

 black matter, or of any peculiar substance save the profusion of oily matter. The amount 

 of thickening in the masses of connective tissue rendered it probable that a certain 

 amount of elephantoid condition had coincided with the pathological changes proper 

 to the disease under consideration, and the distortion of the foot was in this case to 

 be ascribed in great part to this, although, no doubt, the action of the tendons and 

 muscles on the softened fatty bones also contributed to cause the distortion. 



Careful microscopical examinations were made of all the tissues and materials present, 

 but in no case did they afford the faintest evidence of the presence of any fungal or 



Fig. 6. — Section of a foot affected with the Pale Variety of the disease. 



fungoid bodies or of anything save degenerations of the normal elements of the 

 tissues. 



Specimen II. — This preparation, which has already been referred to by Dr. Fayrer 

 in his " Clinical and Pathological Observations in India," consisted of a foot and ankle. 



The foot was much distorted : there was great thickening anteriorly, and the two 

 were elevated and curved upwards from their bases. Numerous crater-like openings 

 on the surface communicated with channels, lined by smooth membrane and leading 

 into the interior of the foot. It was carefully divided longitudinally, the knife passing 

 readily through the bones of the tarsus. As may be observed in the accompanying figure 

 of the specimen (Fig. 6), the line of section passed through the centre of the os calcis 

 posteriorly, and between the second and third toes anteriorly, passing between the meta- 

 tarsal bones of these toes and through the remains of the middle cuneiform and scaphoid 

 bones. On examining the divided surfaces, the foot was seen to be greatly thickening 



