352 The Fungus Disease of India. [part ii. 



of isolated dull, yellowish, more or less spherical bodies of hnn waxy consistence 

 {vide Plate XXVII, Fig. 5). They were easily compressible, and spread out into a greasy 

 smear on the surface of the glass on which they were examined. Both as regards 

 microscopical appearance and effects of reagents they coincided exactly with the 

 ceruminous masses of the previous specimen (pages 350-1) or with the nuclei of the 

 common roe-like particles. The subcutaneous fat was carefully examined under a low 

 magnifying power, and a sprinkling of similar bodies was detected in and removed 

 from it. It was quite evident that they were local degenerations of portions of the 

 normal fatty tissue, lobules or aggregations of fat cells being discovered in various 

 stages of modification from mere slight condensation of the contents of the cells 

 up to the formation of firm, waxy grains or concretions, which, in the more advanced 

 cases, had lost all organic connection with the surrounding tissues, and were manifestly 

 only capable of acting as foreign bodies (Plate XXVII, Figs. 5-6). 



Microscopic examinations here too failed to show any traces of the presence of 

 vegetable organisms, the degenerated material consisting solely of waxy, amorphous 

 matter. No distinct roe-like particles were to be found by the unaided senses, and 

 the microscope showed an entire absence of fringes or other crystalline forms in con- 

 nection with the concretions. In this case the degeneration was evidently merely 

 commencing, and had not yet advanced so far as to pass on to the formation of 

 crystals, but as the case was one of comparatively short duration — the patient had 

 only suffered from the disease for one year — this was only what might, perhaps, have 

 been expected, and the probability is that the absence of the characteristic roe-like 

 particles was due to this and not to any peculiarity in the morbid process. 



Specimen V. — A collection of the roe-like particles discharged from the foot in a 

 case previous to amputation. 



These presented no special peculiarities, and were composed of the usual aggre- 

 gations of masses of fatty matter of waxy consistence fringed with feathery crystals. 

 No signs of fungal or other vegetable elements could be detected in them. 



Specimen VI. — A specimen of diseased tissues from a foot, comprising both bones 

 and soft parts, which had been dried in the sun. This was obtained in order to 

 provide materials for cultivation, and presented nothing in any way peculiar. It con- 

 tained an abundance of the characteristic roe-like bodies, and, as usual, was devoid of 

 all fungal elements. 



Specimen VII. — This consisted of transverse sections through the lower portion of 

 the leg in a case of this form of the disease. 



All the fatty and fibrous tissues were extremely gelatinous, and the preparations 

 were characterised by an extreme profusion of minute, bright rose-coloured bodies, 

 which were sprinkled over the surface of the tissues and formed an abundant deposit 

 at the bottom of the fluid in which the specimen was preserved. They were so 

 abundant as to give the sections the appearance of having been sprinkled with red 

 pepper, and at once to attract attention to their presence even whilst still in the 



