PART II.] Minute Anatomy of Delhi Form of " Oriental Sore.'' 



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2. That these cells are embedded in a cement-substance not readily detected in 

 fresh preparations, but becoming firmer and less translucent by the action of spirit 

 and other preservative media. 



3. That, as in ordinary adenoid tissue, the corpuscular bodies may be brushed out 

 of the meshes of the substance in which they are embedded. 



4. That the cells are frequently observed to be arranged linearly, four or five 

 corpuscles being placed in a row with, very frequently, a delicate string of fibrous tissue 

 on either side. 



5. That the corpuscles vary in appearance from mere irregular lumps of plasma 

 to well-formed lymphoid cells, in such intimate relation with which, as almost to be 



Fig. 23. — Section of a portion of a " Delhi Sore" which had been preserved in spirit and weak 

 chromic acid— x 850 (Hartnack's Obj. No. 9 immersion). 



suggestive of organic connection, are spindle-shaped and epidermoid cells in various 

 grades of transition. 



6. That the lymphoid corpuscles are found in intimate relation with the adventitia 

 of the vascular tissues, notably those of the lymphatics of the corium, and that they 

 tend to become aggregated into " colonies " of various size. 



7. And finally, that the cells becoming pushed forward by the subjacent growth 

 of others, gradually find their way to the surface through rents in the papillae (vide Fig. 22). 



Such are the salient points which! we have been able to observe in connection with 

 the minute anatomy of the Delhi form of the Oriental sore.* 



* During our stay at Delhi we made several attempts to transfer the disease to dogs by means of 

 inoculations of perfectly fresh material derived both from the surface and substance of typical examples of 

 the complaint ; and made counter experiments by irritating small surfaces of healthy skin with acid and with 

 iodine. The results were not such as to call for any detailed account. We found that the irritated surfaces, 

 no matter how induced, ran a somewhat similar course — the purely chemical irritants being to all appearances 

 as deleterious as the matter obtained from the sore. The microscopical elements of which these artificially 

 induced little ulcers consisted were identical. 



