PART III.] Method of detecting the Hcematozoon during Life. 511J 



consistence, whereas the mucous surface of the duodenum presented a mammilated 

 and congested appearance. The jejunum and ileum in the upper half were healthy, 

 but in the lower half of the latter the Peyer's patches were prominent, and the surface 

 covered with minute ulcers ; the glandules infiltrated with a yellowish-white, soft, 

 tubercular-like substance ; the edges of the ulcers thickened and containing similar 

 yellowish-white granular matter. The lining membrane of the caecum and ascending 

 colon was of a bright pink colour, and exhibited five or six circular ulcers about the 

 size of half a pea, with raised and opaque white edges. The entire contents of the 

 intestines consisted only of about a couple of ounces of a pea-soup-like fluid. The 

 mesenteric glands were unaffected. 



The liver was soft and fatty, otherwise normal in appearance ; no reaction with 

 iodine. The gall-bladder was almost empty, containing only a little thin ochre-coloured 

 bile. The spleen seemed to be healthy, as did the uterus and ovaries ; the former 

 was small and unimpregnated. The kidneys presented nothing abnormal to the naked 

 eye ; the right and left weighed respectively 3 ounces 4 drachms and 3 ounces 6 drachms: 

 these, together with the super-renal capsules, were placed in spirit and kindly forwarded 

 by Dr. McConnell for my examination, the result of which will be referred to further 

 on (page 519). 



As in other cases of Chyluria on record, so in this, not the remotest clue is afforded 

 as to the nature, or as to the cause, of the disease by the 'post-mortem appearances 

 visible to the naked eye ; nor is there any sufficiently-marked lesion to account for 

 the condition of the urine during life, nor for the rapid manner in which the patient 

 ultimately succumbed. 



In order to detect the Hgematozoon during life, the method adopted by me is 

 as follows : — A piece of narrow tape is coiled tightly round the end of one of the 

 fingers or toes, so as to produce a little temporary local congestion of the part, but 

 not to such an extent as to cause the slightest pain ; and with a clean, finely-pointed 

 needle the finger is gently pricked — half-a-dozen slides and covering glasses having 

 been previously prepared. The drop of blood thus obtained will suffice for several 

 slides, but I find it a good plan to squeeze out only a very small drop, and transfer 

 it altogether to one slide by drawing the edge of the covering glass along the tip 

 of the finger so as to scrape off the " droplet." The glass is then carefully pressed on to 

 the slide by a gliding motion, in order to produce as thin a layer of fluid as possible, 

 and to ensure that all the fluid removed is retained beneath the cover, because there is a 

 tendency on the part of the fluid to carry the Hsematozoa towards the edge of the 

 slide, just as is observed to take place in examinations of the urine for " casts " of 

 the kidney-tubules. 



The slides are now to be carefully and systematically examined; a lateral and 

 horizontal stage-movement being very useful for this purpose, as it enables us to make 

 sure that every part of the preparation has been scrutinized. 



