y 



532 A HcEmatozoon in Human Blood. [part hi. 



Chyluria, the third attack within the last two years, but as yet not complicated 

 with any other disease. In this person's blood, also, Filarise were very numerous — 

 each slide containing two, three, or more specimens. 



For the opportunity of examining the two persons above referred to, I am again 

 indebted to my friend Dr. J. F. P. McConnell, among whose out-patients, at the 

 Medical College Hospital, the cases occurred. 



A week or so later Dr. Kenneth McLeod, Professor of Anatomy at the Medical 

 College, very kindly forwarded for my examination about three ounces of a reddish- 

 brown fluid, emitting a faint, but not disagreeable, odour, of slightly alkaline 

 reaction, and with a specific gravity of 1022. After standing awhile the reddish 

 colour matter partially subsided ; the upper layer assumed a chyle-like aspect and 

 formed an imperfect coagulum. 



This fluid had exuded, through minute orifices, from soft tubercular elevations 

 on the surface of the scrotum of a native patient. The scrotum is described as 

 presenting a sponge-like aspect, especially on the left side, and is covered with 

 yielding prominences from which fluid may constantly be squeezed — a condition 

 which appears to have existed about three years. On subjecting the sediment of 

 this fluid to microscopic examination, numerous living FilarisB were readily detected. 



This adds another to the list of cases showing the intimate connection which 

 exists between the presence of this parasite and such diseases as appear to imply 

 some abnormality of the lymphatic system in tropical climates. 



Dr. McLeod promises to publish full details of this very interesting case at no 

 distant period. 



Almost at the same time another person— the fifth suffering from this class of 

 disease brought to my notice within a month — was kindly sent to me by Dr. Henry 

 Cayley, Surgeon to the Chandney Hospital. He was an East Indian, bom and 

 brought up at Madras, and suff'ering from a sixth attack of Chyluria. The first 

 came on suddenly in September 1871, after a residence of two years at Coconada ; 

 and each subsequent attack has lasted about two months — the disease appearing 

 and disappearing at irregular periods. He complains of great debility and thirst, and 

 of a dull pain on the under surface of the scrotum, but he is able to attend to his 

 duties as a clerk. 



Eight slides of blood were prepared ; four being obtained from each hand by 

 means of a needle. Within a comparatively short time two dozen Hsematozoa were 

 counted in the eight preparations in a state of great activity. They were also present 

 in the urine. 



It will be observed that these Filarise have now been traced directly to the 

 blood in ten, and detected in one or other of the various tissues and secretions of 

 the body in at least thirty individuals ; and always associated with Chyluria, Ele- 

 phantiasis, or some such, closely allied, pathological condition. 



