PART III.] Phenomena Associated with Nematode Hcsmatozoa in Man. 549 



numerous specimens of the Filaria sanguinis hominis. He thereupon most kindly 

 came to me, bringing some specimens with him, and invited me to make a minute 

 examination of the body which had been specially set aside for the purpose. 



On the following morning, some thirty-six hours after death, I made a careful 

 examination of all the organs in siht, but failed to detect any mature parasite. The 

 surface of the entire body was examined to make sure of the absence of such parasites as 

 the Gruinea-worm, as far as external marks would be a guide, but nothing was found 



All the organs were preserved in spirit, as were also specimens of the various tissues 

 of the body. I have since examined the heart with its vessels ; the lungs ; the 

 liver ; the spleen ; the kidneys, and their excretory ducts ; the bladder ; the intes- 

 tines ; the brain, ete. ; but have not, as yet, been able to detect any mature para- 

 site — the embryo-Filarise, however, were present everywhere in abundance. I regret 

 that the final result of the examination cannot be recorded at present as the press 

 cannot be delayed ; but the fact that I have already spent two whole days in making 

 the examination will be sufficient to show that it was more than a cursory one. 



What are the salient morbid phenomena associated with the presence of nematode 

 Haematozoa in man ? As far as my experience has hitherto extended, they may be 

 described as diseased conditions referable to the escape of the nutritive fluids of 

 the body out of their proper channels into some organ or into the cellular tissue, or of 

 obstruction to their fluid — the fluid extravasated being chylous, sanguineous, or a com- 

 bination of the two. 



Speaking generally, these morbid conditions may be described as manifesting them- 

 selves in two principal forms : — 



1. As an exudation or extravasation into some excretory tract — especially the | 



urinary : 



2. As an exudation or extravasation into the subcutaneous tissues. 



/l.")With reference to the escape of nutritive fluid into the urinary tract, it may be 

 stated that, in addition to the fifteen cases of the diseased state commonly known as 

 " Chyluria," described at length in the previous report on this subject, about fifteen more 

 cases of the aff'ection have come under my notice, so that ample opportunities have 

 been afforded for putting the observations then recorded to the test. In these, as in the 

 former cases, Filarice were invariably detected, either in the blood, the urine, or in both.* 

 The malady is not so very rare as is commonly supposed ; indeed, on one occasion, as 

 many as five fresh cases came under my notice within a single month. Some of these 

 are of special interest, as illustrating peculiarities in the disease which were not evident 

 in the cases previously recorded. 



For one of the first cases which came under my notice since the publication of the 

 first series of these observations I am indebted to Dr. Charles Macnamara. The patient 

 was a house-keeper, age 52, the mother of six children, of whom two only are living. 



* One of the persons afiEected in this manner had been a Leper for several years previous to the advent of 

 Chyluria, 



