572 WILL AND 



perfectly well. Towards the close of the day following, on which 

 there were signs of inflammatory irritation and suppuration, it 

 began to suffer from chronic spasms of the left angle of the mouth 

 and left arm, which recurred repeatedly, and rapidly assumed an 

 epileptiform character, affecting the whole of the left side of the 

 body. Next day left hemiplegia had become established, the angle 

 of the mouth drawn to the right, the left cheek-pouch flaccid and 

 distended with food, which had accumulated outside the dental 

 arch ; there being almost total paralysis of the left arm, and partial 

 paralysis of the left leg. On the day following the paralysis of 

 motion was complete over the whole of the left side, and continued 

 so till death, nine days subsequently. Tactile sensation, as well as 

 sight, hearing, smell and taste were retained. On jpost-mortem 

 examination it was found that the exposed convolutions were com- 

 pletely softened, but beyond this the rest of the hemisphere and 



the basal ganglia were free from organic injury In this 



we have a clear case, first, of vital irritation producing precisely 

 the same effects as the electric current, and then destruction by 

 inflammatory softening, resulting in complete paralysis of volun- 

 tary motion on the opposite side of the body, without affection of 

 sensation." 



The important observation previously made by Hngli- 

 lings Jackson that irritative disease of the corresponding 

 region of the Brain, or of some part of it, in the human 

 subject, is specially apt to be associated with a liability to 

 unilateral convulsions, complete or partial, of the opposite 

 side of the body, was thus verified so far as it could be by 

 these experimental observations upon the Monkey. There 

 is reason for believing, also, that destructive disease of 

 the Cerebral Convolutions in this region may lead, in the 

 human subject, as it did in the monkey, to a condition 

 of complete Hemiplegia. In each, therefore, both in 

 man and monkey, irritation of certain surface regions of 

 one of the Cerebral Hemispheres is followed by choreiform 

 twitchings or by actual Convulsions on the opposite side 

 of the body, whilst destruction of the same parts is fol- 

 lowed by an opposite unilateral Paralysis. Irritation and 



