430 THE CHEMISTRY OF TUMORS 



or, indeed, equals this quantity. It seems improbable that so 

 little tumor tissue can form so much urinary proteid, and 

 Magnus-Levy suggests that it must come from the food pro- 

 teids as a result of altered proteid metabolism. Against this 

 view, however, are the following facts : (1) The Bence-Jones 

 body has been found (but not constantly) in the myeloma 

 tissue, but not in other organs or tissues ; (2) the quantity 

 in the urine is not dependent upon diet ; l (3) it is associated 

 only with this form of tumor. Simon considers it probable 

 that the proteid is formed from serum-globulin, perhaps by 

 an enzymatic action of the tumor cells, and once formed, it is 

 rapidly eliminated by the kidneys, as are all foreign proteids. 



1 See Allard and Weber, Deut. med. Woch., 1906 (32), 1251. Voit and 

 Salyendi (Munch, med. Woch., 1904 (51), 1281), however, report a case in 

 which diet modified the elimination of the " albumose." 



