POST-MORTEM EXAMINATION 51 



*' Inoculation experiments performed on the 

 small animals of the laboratory showed that the 

 acid-fast bacilli were not those of tuberculosis." 



M'Fadyean, Sheather, and Edwards, give the follow- 

 ing details of a post-mortem examination of a Welsh 

 ewe, examined in April, 191 2 : 



"A considerable number of worms {Strongyhts 

 cervicornis) were found in the abomasum, which 

 was nearly empty, but no abnormal appearance 

 of the mucous membrane was observed. The 

 large and small intestines were slit up along their 

 entire length and searched for worm parasites. 

 One tapeworm was found. 



'* There was distinct thickening of the wall in 

 the case of the large intestine, this being most 

 marked in the caecum ; there was also some 

 irregular wrinkling in this position. The thicken- 

 ing, although not so pronounced, was continued 

 throughout the large intestine. The posterior half 

 of the small intestine was appreciably thicker than 

 normal, and at some places there was abnormal 

 permanent wrinkling, though not so marked as is 

 usually the case in cattle. 



" Microscopic Examination of Smears. — This 

 showed a rich invasion of the intestinal mucous 

 membrane with small acid-fast bacilli quite indis- 

 tinguishable from those usually found in Johne's 

 disease of cattle. . . . The smear taken from the 

 caecum proved to be extraordinarily rich." 



Bacilli were found in parts of the small intestine, 

 but onl}^ a few in the colon. 



In two sheep, which the present writers inoculated 

 with pure cultures of Johne's bacillus isolated from 

 a cow, and which were killed ten weeks later — after 



