418 A MANUAL OF BACTERIOLOGY 



grown in serum or blood broth in shallow layers. After acclimatisa- 

 tion to artificial media it will develop on the ordinary laboratory 

 media. 



The B. pertussis is agglutinated feebly by the blood of patients, 

 but complement-fixation is marked. 



Monkeys are stated to develop a typical whooping-cough on 

 inoculation, but the ordinary laboratory animals are susceptible 

 only to massive intraperitoneal or intravenous inoculation, death 

 ensuing from a septicaemic process. 



Attempts have been made to treat the disease with a vaccine. 



