544 A MANUAL OF BACTERIOLOGY 



but does not seem to be transmissible to other animals. 

 The salivary and some of the lymphatic glands contain 

 the virus. 



Flexner has observed a case of spontaneous infection 

 in the monkey, and found that the naso-pharyngeal 

 mucosawas infective, so that this is probably the channel of 

 infection in man. Flies belonging to the genus Stomoxys 

 are stated to be capable of transmitting infection. Human 

 cerebro-spinal fluid was not found infective in some 

 instances, but monkey cerebro-spinal fluid is infective 

 (infectivity in this case may depend on the stage of the 

 disease). 



Human ascitic fluid inoculated with the filtered fluid 

 from emulsions of cord became turbid, but no organism 

 could be detected microscopically, and the culture can 

 be carried on from tube to tube (Flexner and Noguchi). 

 Monkeys which have recovered from an attack are refrac- 

 tory to inoculation. A certain degree of active immunity 

 may be established by subcutaneous injection of the virus. 

 The serum of immunised and recovered animals possesses 

 considerable neutralising power for the virus. Attempts 

 are now being made to prepare a curative serum. 



Some cases of the acute ascending paralysis of Landry 

 may be forms of this disease (see also p. 535). 



Buzzard, from a case of the latter disease, isolated a 

 coccus which induced a rapidly spreading palsy on sub- 

 dural inoculation into rabbits. 



Typhus Fever l 



Many organisms have been described in this disease. 

 Nicolle, in Tunis, has found that typhus fever of man 

 is communicable to the chimpanzee by inoculation and 

 from the anthropoid to the Chinese bonnet monkey. 



1 See Hewlett, Practitioner, July 1911, p. 112 (Refs.). 



