CULTIVATION OF ACTINOMYCES. 



289 



to find leucocytes in the neighbourhood of a colony con- 

 taining small portions of the filaments in their interior. 



In the ox, on the other hand, the disease usually remains 

 quite local, or spreads by continuity. It may produce 

 tumour-like masses in the region of the jaw or neck, or it 

 may specially affect 

 the palate or tongue, 

 in the latterproducing 

 enlargement and in- 

 duration, with nodular 

 thickening on the sur- 

 face the condition 

 known as " woody 

 tongue." 



Source of the Para- 

 site. There is a con- 

 siderable amount of 

 evidence to show that 

 outside the body the 

 parasite grows on 

 grain, especially on 

 barley. Both in the 

 ox and in the pig the 

 parasite has been 

 found growing around 

 fragments of grain 

 embedded in the 

 tissues. There are A B 



besides, in the Case FIG. 76. Cultures of the actinomyces on 

 of the human Sub- glycerine agar, of about three weeks' growth ; 

 iect a certain number snow ^ n S the appearances which occur. The 

 , . , growth in A is at places somewhat corrugated 

 Ot cases m which O n the surface. Natural size, 

 there was a history 



of penetration of a mucous surface by a portion of grain, 

 and in a considerable proportion of cases the patient has 

 been exposed to infection from this source. The position 

 of the lesions in cattle is also in favour of such a view. 

 The conditions of growth outside the body in a natural 

 19 





