LESIONS IN THE HUMAN SUBJECT 185 



In pyaemia they are frequently present, though in most cases 

 associated with other pyogenic organisms. Some cases of 

 enteritis in infants streptococcic enteritis are also apparently 

 due to a streptococcus, which, however, presents in cultures 

 certain points of difference from the streptococcus pyogenes. 



The bacillus coli communis is found in a great many inflam- 

 matory and suppurative conditions in connection with the ali- 

 mentary tract for example, in suppuration in the peritoneum, 

 or in the extraperitoneal tissue with or without perforation of the 

 bowel, in the peritonitis following strangulation of the bowel, in 

 appendicitis and the lesions following it, in suppuration around 

 the bile-ducts, etc. It may also occur in lesions in other parts 

 of the body, endocarditis, pleurisy, etc., which in some cases 

 are associated with lesions of the intestine, though in others such 

 cannot be found. It is also frequently present in inflammation 

 of the urinary passages, cystitis, pyelitis, abscesses in the kidneys, 

 etc., these lesions being in fact most frequently caused by this 

 or closely allied organisms. 



In certain cases o enteritis it is probably the causal agent, 

 though this is difficult of proof, as it is much increased in 

 numbers in practically all abnormal conditions of the intestine. 

 We may remark that it has been repeatedly proved that the 

 bacillus coli cultivated from various lesions is more virulent than 

 that in the intestine, its virulence having been heightened by 

 growth .in the tissues. 



The micrococcus tetragenus is often found in suppurations in 

 the region of the mouth or in the neck, and also occurs in 

 various lesions of the respiratory tract, in phthisical cavities, 

 abscesses in the lungs, etc. Sometimes it is present alone, and 

 probably has a pyogenic action in the human subject under 

 certain conditions. In other cases it is associated with other 

 organisms. Recently one or two cases of pyaemia have been 

 described in which this organism was found in a state of purity 

 in the pus in various situations. In this latter condition the pus 

 has been described as possessing an oily, viscous character, and 

 as being often blood-stained. 



The bacillus pyocyaneus is rarely found alone in pus, though 

 it is not infrequent along with other organisms. We have met 

 with it twice in cases of multiple abscesses, in association with 

 the staphylococcus pyogenes aureus. Lately some diseases in 

 children have been described in which the bacillus pyocyaneus 

 has been found throughout the body ; in these cases the chief 

 symptoms have been fever, gastro-intestinal irritation, pustular 

 or petechial eruptions on the skin, and general marasmus. 



