BORIC ACID AND BORAX. 63 



on March 2. No other departures from the normal are noted for the 

 first subperiod (February 28 to March 3, inclusive). On March 5, 

 during the second subperiod, a headache and feeling of fullness in the- 

 stomach are developed, but the symptoms are not sufficiently marked 

 to cause any disturbance in the ordinary functions of the body. On 

 March 7, the last day of the second subperiod, additional symptoms of 

 disturbance of digestion are noted in the form of severe pains in the 

 stomach and intestines. On March 8 decided symptoms of malaise 

 and indisposition and loss of appetite, including pains in the head and 

 the intestines, are developed. On the next day there is a very severe 

 dizzy headache and continued pain in the intestines during the whole 

 of the day. There is, however, no increase of temperature and no 

 diarrhea. The headache and pains persist, the headache especially 

 being very severe on March 10, with a slight febrile excitement, the 

 recorded temperatures being 98.8 and 99 F. The headache increases 

 in intensity during the llth, and there is a marked rise of tempera- 

 ture, the recorded observations being 100.2 and 100.2 F. and the 

 pulsations 98 and 92, respectively, before and after dinner. This 

 subject is in a rather bad condition at the end of the third subperiod. 

 The quantity of boric acid taken during these periods is 1 gram a da} 7 

 during the first period of four days, 4 grams during the first two 

 days of the second period of four days and 2 grams the other two 

 days, and 3 grams during the first and third days of the third period 

 and 2 grams the other two days. The exhibition of boric acid is 

 discontinued on March 11. 



On March 12, the first day of the after period, there is still con- 

 siderable headache, and a slight hemorrhage from the nostrils at 6 a. m. 

 The temperature, however, has declined, but is still above the normal, 

 being 99.6 and 99.8 F. Headache and bad feeling have largely 

 passed away on the 13th, and the temperature has also fallen, the 

 registrations being 99.1 and 99.1 F. On the 15th the temperature 

 is again almost normal, the registrations being 98. 7 and 98.8 F. and 

 the pulsations 63 and 67 per minute, respectively, before and after 

 dinner. The headache, pains in the intestines, and general feeling of 

 malaise have almost disappeared. On the 16th the normal condition 

 of the body apparently is restored, but there is a slight bleeding of 

 the nose. 



On March 19, the last day.of the after period, the recorded temper- 

 atures are 98.6 and 98.8 F. and the pulsations 60 and 64 per minute, 

 respectively, before arid after dinner. The normal feeling of health 

 is apparently completely restored. In this case it is highly probable 

 that the headache, pains in the stomach, and general ill feeling expe- 

 rienced during the preservative period are chiefly attributable to the 

 efl'ect of the preservative and are not due to any incidental abnormal 

 condition. 



