BORIC ACID AND BORAX. 73 



cold, which was contracted several days previous, is of sufficient 

 importance to be mentioned by No. 11. It is not very marked in 

 character, but is described as an extremely light attack. Apparently 

 it has produced no febrile excitement and very little or no disturbance 

 of the body functions. On March 30 the cold is worse and consider- 

 able fever has developed, the temperature rising to 101.2 F. Six 

 grains of quinine are taken and the subject remains in bed during all 

 of the afternoon of the 30th. The symptoms are very much better 

 on the 1st of April, the temperature being almost normal; but a slight 

 diarrhea has set in, three movements of the bowels being recorded 

 during the day, all of them of a watery nature. During the day, also, 

 12 grains of quinine are taken 4 grains before each meal. By reason 

 of the development of the cold no borax is given No. 11 after the 29th 

 of March until the 4th of April, on which day the normal functions of 

 the body appear to have been restored, the temperatures recorded 

 being 98.8 and 98.8 F. and the pulsations 78 and 78, respectively. 

 Borax is then administered regularly from dinner on the 4th until the 

 close of the preservative per-iod, April 14, with gradually increasing 

 doses from one-half gram on the 4th to 3 grains on the 14th. During 

 this period there are no variations of any marked nature, either in the 

 temperature or the rate of pulsations, nor is there any tendency either 

 to diarrhea or to constipation, the feces having been voided regularly 

 once a day during the whole of the period. There is developed a 

 marked sense of fullness in the head and heaviness of the stomach, 

 accompanied with an impairment of appetite, but not sufficient to 

 cause the subject to refuse to eat any of his regular rations. These 

 symptoms become less marked and finally pass away when the preser- 

 vative ceases to appear in the urine. 



The data, as a whole, are not very conclusive, but show a slight 

 tendency, which seems to be due to the added preservative, to produce 

 heaviness and dullness in the head, a slight loss of appetite, and a gen- 

 eral feeling of malaise. The data, however, are not entirely definite in 

 this respect. 



No. 12 B. J. T. 



All the data observed at the beginning of the fore period on March 

 20 show a normal state with the possible exception of a very slight 

 febrile rdovement, the recorded temperatures being about four-tenths 

 of 1 above the normal and the pulsations being recorded as 96 and 

 88 per minute on the 20th, and 98 and 98 per minute on the 21st, the 

 temperatures for the latter date being recorded as 98.9 and 98.6 

 F. This disturbance, however, is not marked enough to be called any 

 notable departure from the normal state. The functions of the body 

 are discharged in a thoroughly normal way during all of the fore 

 period, the recorded data on March 27, the last day of the fore period, 



